A twin study of cognitive function in chronic fatigue syndrome: the effects of sudden illness onset.

A twin study of cognitive function in chronic fatigue syndrome: the effects of sudden illness onset. Research Abstract Details 

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A twin study of cognitive function in chronic fatigue syndrome: the effects of sudden illness onset. Abstract Text:

Keith H Claypoole,Carolyn Noonan,Roderick K Mahurin,Jack Goldberg,Tom Erickson,Dedra Buchwald,

Variable reports of neuropsychological deficits in individuals with chronic fatigue syndrome (CFS) may, in part, be attributable to methodological limitations. In this study, these limitations were addressed by controlling for genetic and environmental influences and by assessing the effects of comorbid depression and mode of illness onset. Specifically, the researchers conducted a co-twin control study of 22 pairs of monozygotic twins, in which 1 twin met strict criteria for CFS and the co-twin was healthy. Twins underwent a structured psychiatric interview and comprehensive neuropsychological assessment evaluating 6 cognitive domains. Results indicated that twin groups had similar intellectual and visual memory functioning, but fatigued twins exhibited decreases in motor functions (p = .05), speed of information processing (p = .02), verbal memory (p = .02), and executive functioning (p = .01). Major depression did not affect neuropsychological functioning among fatigued twins, although twins with sudden illness onset demonstrated slowed information processing compared with those with gradual onset (p = .01). Sudden onset CFS was associated with reduced speed of information processing. If confirmed, these findings suggest the need to distinguish illness onset in future CFS studies and may have implications for treatment, cognitive rehabilitation, and disability determination.

A twin study of cognitive function in chronic fatigue syndrome: the effects of sudden illness onset. Publishing Authors By Initials

KH Claypoole,C Noonan,RK Mahurin,J Goldberg,T Erickson,D Buchwald,

For similar behavioral disciplines and activities: psychological tests: aptitude tests: intelligence tests: wechsler scales research abstracts see: behavioral disciplines and activities: psychological tests: aptitude tests: intelligence tests: wechsler scales research

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A twin study of cognitive function in chronic fatigue syndrome: the effects of sudden illness onset. Journal Published:

PUBLICATION TYPE: Twin Study

Journal: Neuropsychology

VOLUME: 21

Page Numbers: 507-13

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ISSN: 0894-4105

DAY: 3

MONTH: Jul

YEAR: 2007

A twin study of cognitive function in chronic fatigue syndrome: the effects of sudden illness onset. Information

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LANGUAGE: eng

NlmUniqueID: 8904467

A twin study of cognitive function in chronic fatigue syndrome: the effects of sudden illness onset. Keywords Mesh Terms:

KEYWORDS: Wechsler Scales

MESH TERMS: physiology

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Grant and Affiliation Information for A twin study of cognitive function in chronic fatigue syndrome: the effects of sudden illness onset.

AFFILIATION: Department of Psychology, University of Hawaii, Honolulu, HI, USA.

Country: United States

AGENCY: United States NIAID

GRANT: U19 AI38429

ACRONYM: AI

MEDLINETA: Neuropsychology

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