A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis.

A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis. Abstract Text:

Karen R Steingart,Megan Henry,Suman Laal,Philip C Hopewell,Andrew Ramsay,Dick Menzies,Jane Cunningham,Karin Weldingh,Madhukar Pai,Karen R Steingart,Megan Henry,Suman Laal,Philip C Hopewell,Andrew Ramsay,Dick Menzies,Jane Cunningham,Karin Weldingh,Madhukar Pai,

Conventional diagnostic tests for tuberculosis have several limitations and are often unhelpful in establishing the diagnosis of extrapulmonary tuberculosis. Although commercial serological antibody based tests are available, their usefulness in the diagnosis of extrapulmonary tuberculosis is unknown. A systematic review was conducted to assess the accuracy of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis. In a comprehensive search, 21 studies that reported data on sensitivity and specificity for extrapulmonary tuberculosis were identified. These studies evaluated seven different commercial tests, with Anda-TB IgG accounting for 48% of the studies. The results showed that (1) all commercial tests provided highly variable estimates of sensitivity (range 0.00-1.00) and specificity (range 0.59-1.00) for all extrapulmonary sites combined; (2) the Anda-TB IgG kit showed highly variable sensitivity (range 0.26-1.00) and specificity (range 0.59-1.00) for all extrapulmonary sites combined; (3) for all tests combined, sensitivity estimates for both lymph node tuberculosis (range 0.23-1.00) and pleural tuberculosis (range 0.26-0.59) were poor and inconsistent; and (4) there were no data to determine the accuracy of the tests in children or in patients with HIV infection, the two groups for which the test would be most useful. At present, commercial antibody detection tests for extrapulmonary tuberculosis have no role in clinical care or case detection.

A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis. Publishing Authors By Initials

KR Steingart,M Henry,S Laal,PC Hopewell,A Ramsay,D Menzies,J Cunningham,K Weldingh,M Pai,KR Steingart,M Henry,S Laal,PC Hopewell,A Ramsay,D Menzies,J Cunningham,K Weldingh,M Pai,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Thorax

VOLUME: 62

Page Numbers: 911-8

Journal Abbreviation: Thorax

ISSN: 0040-6376

DAY: 3

MONTH: 08

YEAR: 2007

A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 417353

A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis.

AFFILIATION: Division pf Pulmonary and Critical Care Medicine, San Francisco General Hospital, University of California, USA.

Country: England

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Thorax

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis Related Publications

• A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis.
• A systematic review of commercial serological antibody detection tests for the diagnosis of extrapulmonary tuberculosis.
• Accuracy and reliability of physical signs in the diagnosis of pleural effusion.
• Acquired pulmonary artery branch stenosis caused by pulmonary thromboembolism.
• Acute compartment syndrome after rupture of the medial head of gastrocnemius in a child.
• Ankylosis of primary molar along with congenitally missing first permanent molar.
• Assessment of Left Ventricular Dyssynchrony in Patients With Heart Failure and Normal QRS Duration.
• Atomic model of human Rcd-1 reveals an armadillo-like-repeat protein with in vitro nucleic acid binding properties.
• Commercial serological tests for the diagnosis of tuberculosis: do they work?
• Correction of the inertial effect resulting from a plate moving under low-friction conditions.
• Deficient limb support is a major contributor to age differences in falling.
• Development of HPTLC-UV absorption densitometry method for the analysis of alprazolam and sertraline in combination and its application in the evaluation of marketed preparations.
• Incontinentia pigmenti.
• Interventional approaches to management of pain of oral cancer.
• Medical students reach out for Global health.
• Minimal step length necessary for recovery of forward balance loss with a single step.
• Minimally invasive plate fixation of the tibia.
• Nucleic acid amplification tests for the diagnosis of tuberculous lymphadenitis: a systematic review.
• Optical screening of oral cancer: technology for emerging markets.
• Permanent molars: Delayed development and eruption.
• Predicted threshold against backward balance loss in gait.
• Randomized, double-blind, comparative study of dexrabeprazole 10 mg versus rabeprazole 20 mg in the treatment of gastroesophageal reflux disease.
• Rapid oral fluid-based point-of-care HIV testing: applicability in developing countries.
• SDIF: one year later.
• Synthesis and Biological Activity of N-Substituted-3-chloro-2-azetidinones.
• The branching pattern and communications of the musculocutaneous nerve.
• The socio-cultural challenge in public health interventions: the case of tuberculosis in India.
• Towards high temporal and spatial resolution cardiac imaging with parallel MRI.
• Tuberculosis among health-care workers in low- and middle-income countries: a systematic review.
• [Chromosome microdeletions detected in mental retardation]