A specific glutathione S-transferase isozyme occurring in hereditary hyperbilirubinuria rats.

A specific glutathione S-transferase isozyme occurring in hereditary hyperbilirubinuria rats. Research Abstract Details 

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A specific glutathione S-transferase isozyme occurring in hereditary hyperbilirubinuria rats. Abstract Text:

T Igarashi,T Tsuchiya,T Satoh,

A glutathione S-transferase isozyme which is absent in normal rat liver has been isolated from the hereditary hyperbilirubinuria rat liver cytosol. The enzyme was purified to apparent homogeneity by GSH-affinity chromatography and HPLC on CM-Sepharose CL-6B. It is a heterodimer of two non-identical subunits, i.e., subunit 2 and a previously uncharacterized subunit referred to here as subunit Yx. Immunoblot analysis indicated that GST 2-Yx belongs to the alpha class. GST 2-Yx is characterized by its 4-fold higher activity towards 4-hydroxy-non-2-enal, compared to that of GST 2-2.

A specific glutathione S-transferase isozyme occurring in hereditary hyperbilirubinuria rats. Publishing Authors By Initials

T Igarashi,T Tsuchiya,T Satoh,

For similar animals: chordata: vertebrates: mammals: rodentia: muridae: murinae: rats research abstracts see: animals: chordata: vertebrates: mammals: rodentia: muridae: murinae: rats research

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A specific glutathione S-transferase isozyme occurring in hereditary hyperbilirubinuria rats. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of biochemistry

VOLUME: 109

Page Numbers: 3-5

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Jan

YEAR: 1991

A specific glutathione S-transferase isozyme occurring in hereditary hyperbilirubinuria rats. Information

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LANGUAGE: eng

NlmUniqueID: 376600

A specific glutathione S-transferase isozyme occurring in hereditary hyperbilirubinuria rats. Keywords Mesh Terms:

KEYWORDS: Rats

MESH TERMS: enzymology

Chemical & Substance for Abstract: A specific glutathione S-transferase isozyme occurring in hereditary hyperbilirubinuria rats. Information

Substance Name: Glutathione Transferase

Registry Number: EC 2.5.1.18

Grant and Affiliation Information for A specific glutathione S-transferase isozyme occurring in hereditary hyperbilirubinuria rats.

AFFILIATION: Laboratory of Biochemical Pharmacology and Biotoxicology, Faculty of Pharmaceutical Sciences, Chiba University.

Country: JAPAN

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MEDLINETA: J Biochem

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