A simple molecular mathematical model of mammalian hibernation.

A simple molecular mathematical model of mammalian hibernation. Research Abstract Details 

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A simple molecular mathematical model of mammalian hibernation. Abstract Text:

Marshall Hampton,Matthew T Andrews,

A simple model of the dynamics of the body temperature of a hibernating mammal is presented. Our model provides a good match to experimental data, showing the interruption of low-temperature torpor bouts with periodic interbout arousals (IBAs). In this paper we present a mathematical model of the molecules that participate in the initiation, regulation, and maintenance of the hibernating state. This model can be used to describe the role of regulatory molecules, signal transducers, downstream target enzymes, structural proteins, or metabolites. Because many of the biochemical mechanisms are unknown, this is a preliminary and largely phenomenological model that we hope will inspire further investigation.

A simple molecular mathematical model of mammalian hibernation. Publishing Authors By Initials

M Hampton,MT Andrews,

For similar environment and public health: environment: environment, controlled: temperature research abstracts see: environment and public health: environment: environment, controlled: temperature research

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A simple molecular mathematical model of mammalian hibernation. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of theoretical biology

VOLUME: 247

Page Numbers: 297-302

Journal Abbreviation: J. Theor. Biol.

ISSN: 0022-5193

DAY: 14

MONTH: 03

YEAR: 2007

A simple molecular mathematical model of mammalian hibernation. Information

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LANGUAGE: eng

NlmUniqueID: 376342

A simple molecular mathematical model of mammalian hibernation. Keywords Mesh Terms:

KEYWORDS: Temperature

MESH TERMS: physiology

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Grant and Affiliation Information for A simple molecular mathematical model of mammalian hibernation.

AFFILIATION: Department of Mathematics and Statistics, University of Minnesota, Duluth, 1117 University Drive, Duluth, MN 55812, USA. mhampton@d.umn.edu

Country: Netherlands

AGENCY: United States NHLBI

GRANT: HL-081100

ACRONYM: HL

MEDLINETA: J Theor Biol

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