A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro.

A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro. Abstract Text:

R Barker,S Dunnett,J Fawcett,

Rat chromaffin cells display phenotypic plasticity postnatally. In the presence of glucocorticoids, they retain a chromaffin cell phenotype, whilst in the presence of nerve growth factor and the absence of glucocorticoids they adopt a sympathetic neuronal phenotype. The tachykinins have some of the characteristics of a neurotrophic factor and are present in the form of a substance P afferent input in the rat adrenal medulla. We investigated the effects of stable NK1 and NK2 tachykinin receptor agonists, Ava[L-Pro,N-Me-Leu-10]SP7-11 (GR73632) and [Lys-3,Gly-8,R-Lac-Leu-9]NKA3-10 (GR64349), respectively, on the survival and phenotype of P5-7 rat chromaffin cells in vitro. GR73632 promoted neurite outgrowth, characteristic of the sympathetic neuronal phenotype, in the absence of NGF and glucocorticoids, but was without effect on survival after 2 weeks in culture. GR64349 was without effect.

A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro. Publishing Authors By Initials

R Barker,S Dunnett,J Fawcett,

For similar enzymes and coenzymes: enzymes: oxidoreductases: oxygenases: mixed function oxygenases: tyrosine 3-monooxygenase research abstracts see: enzymes and coenzymes: enzymes: oxidoreductases: oxygenases: mixed function oxygenases: tyrosine 3-monooxygenase research

PUBMED ID PMID:

MEDLINE DATE:

A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Experimental brain research. Experimentelle Hirnfo

VOLUME: 92

Page Numbers: 467-72

Journal Abbreviation:

ISSN: 0014-4819

DAY: 15

MONTH: 02

YEAR: 1993

A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 43312

A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro. Keywords Mesh Terms:

KEYWORDS: Tyrosine 3-Monooxygenase

MESH TERMS: metabolism

Chemical & Substance for Abstract: A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro. Information

Substance Name: Tyrosine 3-Monooxygenase

Registry Number: EC 1.14.16.2

Grant and Affiliation Information for A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro.

AFFILIATION: MRC Cambridge Brain Repair Centre, UK.

Country: GERMANY

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Exp Brain Res

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro Related Publications

• A comparative view of sperm ultrastructure.
• A potential role for bone morphogenetic protein signalling in glial cell fate determination following adult central nervous system injury in vivo.
• A risk score for predicting perioperative blood transfusion in liver surgery (Br J Surg 2007; 94: 860-865).
• A selective tachykinin receptor agonist promotes differentiation but not survival of rat chromaffin cells in vitro.
• Allergic contact dermatitis from 4-chloro-2-[methylthio]pyrimidine-5-carboxylic acid ethyl ester and methyl 4-hydroxy-2-hexynoate in a laboratory chemist.
• Antidepressants: partial response in chronic depression.
• Case of rupture of left lower-lobe bronchus with recovery.
• Chondroitinase ABC has a long-lasting effect on chondroitin sulphate glycosaminoglycan content in the injured rat brain.
• Commentary on Hsu L-L (2006) An analysis of clinical teacher behaviour in a nursing practicum in Taiwan. Journal of Clinical Nursing 15, 619-628.
• Drug nephrotoxicity--the significance of cellular mechanisms.
• Expression, Activity and Regulation of CYP3A in Human and Rodent Brain.
• Factors affecting morphine metabolism following major liver resection.
• Gametogenesis in the male: prospects for its control.
• General practitioners and psychological medicine. Their views on a postgraduate course.
• Heparan sulphate proteoglycans in glia and in the normal and injured CNS: expression of sulphotransferases and changes in sulphation.
• Hereditary painful callosities.
• In response to: Fu M.R., McDaniel R.W. & Rhodes V.A. (2007) Measuring symptom occurrence and symptom distress: development of the Symptom Distress Index. Journal of Advanced Nursing 59, 623-634.
• Infection control. An outbreak of innovation.
• Microchannels as axonal amplifiers.
• Modeling scattering from azimuthally symmetric bathymetric features using wavefield superposition.
• Nursing qua nursing: the connection between nursing knowledge and nursing shortages.
• Observations on the blood supply of growing antlers.
• On 'evidence-based practice': purpose of research is to develop theory.
• Repair in the central nervous system.
• Restricted primitive model for electrolyte solutions in contact with solid surface modified by grafted chains: A density functional approach.
• Series approach to modeling ion size effects for asymmetric electrolytes in the diffuse double layer.
• The added value of nursing conceptual model-based research.
• The role of massage therapy in the relief of cancer pain.
• The specificity of the response of preoptic-septal area neurons to estrogen: 17alpha-estradiol versus 17beta-estradiol and the response of extrahypothalamic neurons.
• The use of chewing gum for preventing postoperative ileus.