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A role for stem cell biology in the physiological and pathological aspects of aging.

A role for stem cell biology in the physiological and pathological aspects of aging. Research Abstract Details 

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  • A role for stem cell biology in the physiological and pathological aspects of aging. Abstract Text:

    The stem cell is an essential component of a developmental phenomenon-one of the key components of a program fundamental to organogenesis and the maintenance of homeostasis throughout life. The stem cell confers plasticity to the process. Because aging is part of the developmental arc, an understanding of the stem cell is essential to understanding aging and some of the degenerative conditions that accompany it. Because stem cells may be isolated and manipulated ex vivo and then reimplanted into organs, they may serve a variety of functions. They have the capability of migrating long distances and targeting pathological conditions, of expressing therapeutic genes and responding to cues that shift their differentiation toward deficient lineages. Therefore, stem cells may be used for cell replacement, for therapeutic interventions, and potentially to modify aging.

    A role for stem cell biology in the physiological and pathological aspects of aging. Publishing Authors By Initials

    For similar cells: stem cells research abstracts see: cells: stem cells research

    PUBMED ID PMID:

    MEDLINE DATE:

    A role for stem cell biology in the physiological and pathological aspects of aging. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Journal of the American Geriatrics Society

    VOLUME: 53

    Page Numbers: S287-91

    Journal Abbreviation: J Am Geriatr Soc

    ISSN: 0002-8614

    DAY: 10

    MONTH: Sep

    YEAR: 2005

    A role for stem cell biology in the physiological and pathological aspects of aging. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 7503062

    A role for stem cell biology in the physiological and pathological aspects of aging. Keywords Mesh Terms:

    KEYWORDS: Stem Cells

    MESH TERMS: physiology

    Chemical & Substance for Abstract: A role for stem cell biology in the physiological and pathological aspects of aging. Information

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    Grant and Affiliation Information for A role for stem cell biology in the physiological and pathological aspects of aging.

    AFFILIATION: Burnham Institute, 10901 North Torrey Pines Road, La Jolla, CA 92037, USA. esnyder@burnham.org

    Country: United States

    United States Research PublicationUnited States Research Publication

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    MEDLINETA: J Am Geriatr Soc

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