A review on treatment of bleeding peptic ulcer: a collaborative task of gastroenterologist and surgeon.

A review on treatment of bleeding peptic ulcer: a collaborative task of gastroenterologist and surgeon. Research Abstract Details 

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A review on treatment of bleeding peptic ulcer: a collaborative task of gastroenterologist and surgeon. Abstract Text:

J J Kolkman,S G Meuwissen,

The majority of patients presenting with acute upper gastrointestinal haemorrhage bleed from peptic diseases erosive gastritis and duodenal or gastric ulcers. Early gastroscopy is essential in order to reach a diagnosis, assess the prognosis, and institute appropriate therapy. In a meta-analysis it was shown that H2-antagonists significantly reduced mortality. However, two large, prospective and placebo-controlled studies with famotidine and omeprazole failed to show reduction of rebleeding or death. The value of endoscopic haemostatic therapy in patients with high-risk peptic ulcers (active bleeding and non-bleeding visible vessel) has been firmly established with 75% decrease in rebleeding and operation rate, and a 40% reduction in mortality. Risk factors for an adverse outcome are: elderly patients, concomitant diseases and large ulcers in the posterior duodenal bulb or on the lesser curvature. The mortality for emergency surgery in upper GI bleeding is still 10-50%. The mortality of elective operations is less than 2%. Some studies have reduced mortality by avoiding emergency surgery through early elective surgery in high-risk patients.

A review on treatment of bleeding peptic ulcer: a collaborative task of gastroenterologist and surgeon. Publishing Authors By Initials

JJ Kolkman,SG Meuwissen,

For similar diagnosis: prognosis research abstracts see: diagnosis: prognosis research

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A review on treatment of bleeding peptic ulcer: a collaborative task of gastroenterologist and surgeon. Journal Published:

PUBLICATION TYPE: Review

Journal: Scandinavian journal of gastroenterology. Suppleme

VOLUME: 218

Page Numbers: 16-25

Journal Abbreviation: Scand. J. Gastroenterol. Suppl

ISSN: 0085-5928

DAY: 13

MONTH: 02

YEAR: 1996

A review on treatment of bleeding peptic ulcer: a collaborative task of gastroenterologist and surgeon. Information

Number of References: 100

LANGUAGE: eng

NlmUniqueID: 437034

A review on treatment of bleeding peptic ulcer: a collaborative task of gastroenterologist and surgeon. Keywords Mesh Terms:

KEYWORDS: Prognosis

MESH TERMS: therapy

Chemical & Substance for Abstract: A review on treatment of bleeding peptic ulcer: a collaborative task of gastroenterologist and surgeon. Information

Substance Name: Anti-Ulcer Agents

Registry Number: 0

Grant and Affiliation Information for A review on treatment of bleeding peptic ulcer: a collaborative task of gastroenterologist and surgeon.

AFFILIATION: Dept. of Gastroenterology, University Hospital Vrije Universiteit, Amsterdam, The Netherlands.

Country: NORWAY

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MEDLINETA: Scand J Gastroenterol Suppl

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