A review of the clinical significance of tissue hypoxia measurements in lower extremity wound management.

A review of the clinical significance of tissue hypoxia measurements in lower extremity wound management. Research Abstract Details 

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A review of the clinical significance of tissue hypoxia measurements in lower extremity wound management. Abstract Text:

Daniel Mathieu,Raj Mani,Daniel Mathieu,Raj Mani,

The aim of this paper is to review techniques that are currently available to measure tissue hypoxia in order to benefit the management of wounds. Direct measurement of tissue partial oxygen pressure (PO(2)) is invasive and therefore unappealing in clinical practice. Several techniques (PET scans, MRI derived techniques) are primarily applicable to research rather than clinical applications. Imaging techniques (duplex ultrasonography, arteriography, MRI techniques) are recommended only as part of the workup for revascularisation. Techniques that assess local perfusion include clearance methods, transcutaneous O(2) and CO( 2) pressure measurement, and laser Doppler flowmetry and imaging. These techniques permit interpretation of altered perfusion states. Each technique offers subtly different information concerning microvascular function. All these techniques require strict protocols to derive reliable data. The potential of the promising near infrared reflectance spectroscopy (NIRS) technique is yet to be determined.

A review of the clinical significance of tissue hypoxia measurements in lower extremity wound management. Publishing Authors By Initials

D Mathieu,R Mani,D Mathieu,R Mani,

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A review of the clinical significance of tissue hypoxia measurements in lower extremity wound management. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: The international journal of lower extremity wound

VOLUME: 6

Page Numbers: 273-83

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ISSN: 1534-7346

DAY: 30

MONTH: Dec

YEAR: 2007

A review of the clinical significance of tissue hypoxia measurements in lower extremity wound management. Information

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LANGUAGE: eng

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Grant and Affiliation Information for A review of the clinical significance of tissue hypoxia measurements in lower extremity wound management.

AFFILIATION: Service d'Urgence Respiratoire, de Réanimation Médicale et de Médecine Hyperbare, Hôpital Calmette, Lille, France. dmathieu@chru-lille.fr

Country: United States

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MEDLINETA: Int J Low Extrem Wounds

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