A randomized trial comparing two different approaches of pacemaker selection.

A randomized trial comparing two different approaches of pacemaker selection. Research Abstract Details 

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A randomized trial comparing two different approaches of pacemaker selection. Abstract Text:

M ,B Schaer,C Kaufmann,N Moulay,T Cron,T Cueni,P Weiss,C Schindler,C Sticherling,S Osswald,M ,B Schaer,C Kaufmann,N Moulay,T Cron,T Cueni,P Weiss,C Schindler,C Sticherling,S Osswald,

Aims DDD-pacemakers are favoured in patients with sick-sinus-syndrome or AV-block. However, AAI-pacemakers for sick-sinus-syndrome or VDD-pacemakers for AV-block may provide similar benefit with lower costs. The aim is to show that a tailored approach (TA) with arrhythmia-specific pacemaker selection was equal to a standard approach (SA) regarding quality of life (QoL) at lower costs. Methods and results The study was prospective and randomized with QoL as primary endpoint. Secondary endpoints were a combined endpoint of all-cause mortality, worsening heart failure or angina, atrial fibrillation (AF), stroke, these endpoints individually and costs. Of 198 patients (age 77 +/- 10 years, 43% female, ejection fraction 54 +/- 12%, follow-up 38 +/- 15 months), 94 were randomized to SA and 104 to TA. Thirty-two patients (34%) died in the SA group vs. 25 (24%) in the TA (P= ns). QoL showed no differences in all dimensions. The combined secondary endpoint was reached more frequently with SA (51%) compared to TA (37%, P = 0.045). There was no difference regarding all single secondary endpoints. Hardware costs were reduced by 15% (P < 0.0001). Conclusion In long-term follow-up, a TA is equal to SA regarding the primary endpoint QoL and secondary endpoints as AF and mortality. Depending on the healthcare system, it may significantly reduce costs.

A randomized trial comparing two different approaches of pacemaker selection. Publishing Authors By Initials

M ,B Schaer,C Kaufmann,N Moulay,T Cron,T Cueni,P Weiss,C Schindler,C Sticherling,S Osswald,M ,B Schaer,C Kaufmann,N Moulay,T Cron,T Cueni,P Weiss,C Schindler,C Sticherling,S Osswald,

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A randomized trial comparing two different approaches of pacemaker selection. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Europace : European pacing, arrhythmias, and cardi

VOLUME: 9

Page Numbers: 1185-90

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ISSN: 1099-5129

DAY: 19

MONTH: 10

YEAR: 2007

A randomized trial comparing two different approaches of pacemaker selection. Information

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LANGUAGE: eng

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AFFILIATION: Division of Cardiology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland.

Country: England

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MEDLINETA: Europace

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