A randomized crossover comparative study of aspirin, cilostazol and clopidogrel in normal controls: analysis with quantitative bleeding time and platelet aggregation test.

A randomized crossover comparative study of aspirin, cilostazol and clopidogrel in normal controls: analysis with quantitative bleeding time and platelet aggregation test. Research Abstract Details 

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A randomized crossover comparative study of aspirin, cilostazol and clopidogrel in normal controls: analysis with quantitative bleeding time and platelet aggregation test. Abstract Text:

Joong-Seok Kim,Kwang-Soo Lee,Yeong-In Kim,Yoshiko Tamai,Reiko Nakahata,Hideki Takami,Joong-Seok Kim,Kwang-Soo Lee,Yeong-In Kim,Yoshiko Tamai,Reiko Nakahata,Hideki Takami,

The effects of three antiplatelet drugs, aspirin, clopidogrel and cilostazol, were examined and compared using a quantitative bleeding time (QBT) test apparatus. In 12 healthy adult male subjects, a QBT test and platelet aggregation test were performed before and after medication. Cilostazol was found to be as effective as aspirin and clopidogrel in inhibiting platelet aggregation. Following the oral administration of aspirin and clopidogrel for 7 days, the bleeding time was significantly prolonged. In contrast, none of these QBT parameters were altered by the cilostazol treatment. This suggests that cilostazol has potent efficacy in inhibiting platelet aggregation without prolonging the bleeding time and changing the bleeding pattern.

A randomized crossover comparative study of aspirin, cilostazol and clopidogrel in normal controls: analysis with quantitative bleeding time and platelet aggregation test. Publishing Authors By Initials

JS Kim,KS Lee,YI Kim,Y Tamai,R Nakahata,H Takami,JS Kim,KS Lee,YI Kim,Y Tamai,R Nakahata,H Takami,

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A randomized crossover comparative study of aspirin, cilostazol and clopidogrel in normal controls: analysis with quantitative bleeding time and platelet aggregation test. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of clinical neuroscience : official journa

VOLUME: 11

Page Numbers: 600-2

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ISSN: 0967-5868

DAY: 20

MONTH: Aug

YEAR: 2004

A randomized crossover comparative study of aspirin, cilostazol and clopidogrel in normal controls: analysis with quantitative bleeding time and platelet aggregation test. Information

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LANGUAGE: eng

NlmUniqueID: 9433352

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Grant and Affiliation Information for A randomized crossover comparative study of aspirin, cilostazol and clopidogrel in normal controls: analysis with quantitative bleeding time and platelet aggregation test.

AFFILIATION: Department of Neurology, College of Medicine, The Catholic University of Korea, Korea.

Country: Scotland

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MEDLINETA: J Clin Neurosci

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