A prospective study of green tea consumption and oral cancer incidence in Japan.

A prospective study of green tea consumption and oral cancer incidence in Japan. Research Abstract Details 

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A prospective study of green tea consumption and oral cancer incidence in Japan. Abstract Text:

Reiko Ide,Yoshihisa Fujino,Yoshiharu Hoshiyama,Tetsuya Mizoue,Tatsuhiko Kubo,Truong-Minh Pham,Kiyoyumi Shirane,Noritaka Tokui,Kiyomi Sakata,Akiko Tamakoshi,Takesumi Yoshimura, ,Reiko Ide,Yoshihisa Fujino,Yoshiharu Hoshiyama,Tetsuya Mizoue,Tatsuhiko Kubo,Truong-Minh Pham,Kiyoyumi Shirane,Noritaka Tokui,Kiyomi Sakata,Akiko Tamakoshi,Takesumi Yoshimura, ,

PURPOSE: To examine the relation of green tea consumption with oral carcinogenesis, we prospectively analyzed data from a nationwide large-scale cohort study in Japan. METHODS: A total of 20,550 men and 29,671 women aged 40-79 years, without any history of oral and pharyngeal cancer at baseline survey, were included in the present study. During a mean follow-up period of 10.3 years, 37 oral cancer cases were identified. The Cox proportional hazard model was used to estimate the hazard ratio (HR) and 95% confidence interval (95% CI) for oral cancer according to green tea consumption by sex, while adjusting for age, smoking, alcohol drinking, and other dietary factors. RESULTS: For women, the HRs of oral cancer for green tea consumption of 1-2, 3-4, and 5 or more cups per day were 0.51 (95% CI: 0.10-2.68), 0.60 (95% CI: 0.17-2.10), and 0.31 (95% CI: 0.09-1.07), respectively, compared with those who drank less than one cup per day (p for trend, 0.08). For men, no such trends were observed. CONCLUSIONS: Our findings did not suggest a prominent inverse association of green tea consumption with oral cancer, although there was a tendency for a reduced risk in women.

A prospective study of green tea consumption and oral cancer incidence in Japan. Publishing Authors By Initials

R Ide,Y Fujino,Y Hoshiyama,T Mizoue,T Kubo,TM Pham,K Shirane,N Tokui,K Sakata,A Tamakoshi,T Yoshimura, ,R Ide,Y Fujino,Y Hoshiyama,T Mizoue,T Kubo,TM Pham,K Shirane,N Tokui,K Sakata,A Tamakoshi,T Yoshimura, ,

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A prospective study of green tea consumption and oral cancer incidence in Japan. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Annals of epidemiology

VOLUME: 17

Page Numbers: 821-6

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ISSN: 1047-2797

DAY: 2

MONTH: 07

YEAR: 2007

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LANGUAGE: eng

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AFFILIATION: Department of Clinical Epidemiology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyusyu, Japan. r-ochide@med.uoeh-u.ac.jp

Country: United States

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MEDLINETA: Ann Epidemiol

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