A preliminary study of screening for risk of autism in children with fragile X syndrome: testing two risk cut-offs for the Checklist for Autism in Toddlers.

A preliminary study of screening for risk of autism in children with fragile X syndrome: testing two risk cut-offs for the Checklist for Autism in Toddlers. Research Abstract Details 

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A preliminary study of screening for risk of autism in children with fragile X syndrome: testing two risk cut-offs for the Checklist for Autism in Toddlers. Abstract Text:

D J Scambler,S L Hepburn,R J Hagerman,S J Rogers,

OBJECTIVE: Risk criteria for the Checklist for Autism in Toddlers (CHAT) and modified risk criteria (i.e. the Denver Criteria) were compared in a group of children with fragile X syndrome (FXS) and autism. METHOD: Participants were 17 children aged 2-4 years with DNA confirmation of FXS. Four children had autism and 13 children did not. RESULTS: Preliminary findings regarding the sensitivity and specificity of the CHAT for detecting risk for autism in children with FXS are as follows: using the original CHAT risk criteria, sensitivity and specificity were 50% and 100%, respectively; and using the Denver Criteria, sensitivity and specificity were 75% and 92%, respectively. CONCLUSIONS: The CHAT and the Denver Criteria resulted in preliminary findings suggesting high levels of sensitivity to autism in children with FXS.

A preliminary study of screening for risk of autism in children with fragile X syndrome: testing two risk cut-offs for the Checklist for Autism in Toddlers. Publishing Authors By Initials

DJ Scambler,SL Hepburn,RJ Hagerman,SJ Rogers,

For similar investigative techniques: epidemiologic methods: statistics as topic: sensitivity and specificity research abstracts see: investigative techniques: epidemiologic methods: statistics as topic: sensitivity and specificity research

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A preliminary study of screening for risk of autism in children with fragile X syndrome: testing two risk cut-offs for the Checklist for Autism in Toddlers. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of intellectual disability research : JIDR

VOLUME: 51

Page Numbers: 269-76

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ISSN: 0964-2633

DAY: 3

MONTH: Apr

YEAR: 2007

A preliminary study of screening for risk of autism in children with fragile X syndrome: testing two risk cut-offs for the Checklist for Autism in Toddlers. Information

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LANGUAGE: eng

NlmUniqueID: 9206090

A preliminary study of screening for risk of autism in children with fragile X syndrome: testing two risk cut-offs for the Checklist for Autism in Toddlers. Keywords Mesh Terms:

KEYWORDS: Sensitivity and Specificity

MESH TERMS: methods

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Grant and Affiliation Information for A preliminary study of screening for risk of autism in children with fragile X syndrome: testing two risk cut-offs for the Checklist for Autism in Toddlers.

AFFILIATION: Oklahoma State University, Stillwater, Oklahoma, USA. scambler@okstate.edu

Country: England

AGENCY: United States NICHD

GRANT: P01 HD35468

ACRONYM: HD

MEDLINETA: J Intellect Disabil Res

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