A phosphorimidate rearrangement for the facile and selective preparation of allylic amines.

A phosphorimidate rearrangement for the facile and selective preparation of allylic amines. Research Abstract Details 

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A phosphorimidate rearrangement for the facile and selective preparation of allylic amines. Abstract Text:

Bin Chen,Anna K Mapp,

Allylic phosphorimidates, readily prepared from the combination of an allylic alcohol, an azide, and a chlorophosphite, undergo [3,3]-rearrangement under thermal conditions to provide single isomers of allylic phosphoramidates. This new rearrangement is tolerant of a range of substitution patterns on the reactants. Treatment of the products of the rearrangement with ethanethiolate followed by acid produces a protected allylic amine. This strategy thus provides an attractive and versatile procedure for the preparation of key synthetic intermediates, allylic amines.

A phosphorimidate rearrangement for the facile and selective preparation of allylic amines. Publishing Authors By Initials

B Chen,AK Mapp,

For similar environment and public health: environment: environment, controlled: temperature research abstracts see: environment and public health: environment: environment, controlled: temperature research

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A phosphorimidate rearrangement for the facile and selective preparation of allylic amines. Journal Published:

PUBLICATION TYPE: Research Support, U.S. Gov't,

Journal: Journal of the American Chemical Society

VOLUME: 126

Page Numbers: 5364-5

Journal Abbreviation: J. Am. Chem. Soc.

ISSN: 0002-7863

DAY: 5

MONTH: May

YEAR: 2004

A phosphorimidate rearrangement for the facile and selective preparation of allylic amines. Information

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LANGUAGE: eng

NlmUniqueID: 7503056

A phosphorimidate rearrangement for the facile and selective preparation of allylic amines. Keywords Mesh Terms:

KEYWORDS: Temperature

MESH TERMS: chemistry

Chemical & Substance for Abstract: A phosphorimidate rearrangement for the facile and selective preparation of allylic amines. Information

Substance Name: Organophosphorus Compounds

Registry Number: 0

Grant and Affiliation Information for A phosphorimidate rearrangement for the facile and selective preparation of allylic amines.

AFFILIATION: Department of Chemistry, University of Michigan, Ann Arbor, Michigan 48109, USA.

Country: United States

AGENCY: United States NIGMS

GRANT: GM65330

ACRONYM: GM

MEDLINETA: J Am Chem Soc

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