A partial cDNA encoding 811 amino acids of connectin (titin), a giant elastic protein of muscle (3,000 kDa), was cloned from a chicken embryonic skeletal muscle cDNA library using antibodies to muscle connectin. The encoded product was the C terminal segment of connectin. The predicted sequences consisted of 5 type II motifs (immunoglobulin C2 type) separated by 5 interdomain insertions. One interdomain insertion had significant homology (RSP) to KSP repeats found in human cardiac C-terminal connectin and another had a high sequence homology to porin (67.7%; 31 amino acids).
A partial connectin cDNA encoding a novel type of RSP motifs isolated from chicken embryonic skeletal muscle. Publishing Authors By Initials
A partial connectin cDNA encoding a novel type of RSP motifs isolated from chicken embryonic skeletal muscle. Journal Published:
PUBLICATION TYPE: Research Support, Non-U.S. Gov
Journal: Journal of biochemistry
VOLUME: 115
Page Numbers: 147-9
Journal Abbreviation: J. Biochem.
ISSN: 0021-924X
DAY: 19
MONTH: Jan
YEAR: 1994
A partial connectin cDNA encoding a novel type of RSP motifs isolated from chicken embryonic skeletal muscle. Information
Number of References:
LANGUAGE: eng
NlmUniqueID: 376600
A partial connectin cDNA encoding a novel type of RSP motifs isolated from chicken embryonic skeletal muscle. Keywords Mesh Terms:
KEYWORDS: Sequence Homology, Amino Acid
MESH TERMS: embryology
Chemical & Substance for Abstract: A partial connectin cDNA encoding a novel type of RSP motifs isolated from chicken embryonic skeletal muscle. Information
Substance Name: Protein Kinases
Registry Number: EC 2.7.1.37
Grant and Affiliation Information for A partial connectin cDNA encoding a novel type of RSP motifs isolated from chicken embryonic skeletal muscle.
AFFILIATION: Department of Molecular Biology, Tokyo Metropolitan Institute of Medical Science.
Country: JAPAN
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MEDLINETA: J Biochem
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ACCESSION NUMBER: D16844
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