A new technique for tear film fluorophotometry.

A new technique for tear film fluorophotometry. Research Abstract Details 

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A new technique for tear film fluorophotometry. Abstract Text:

AIM: To develop a reliable and objective non-touch technique for determination of tear volume and tear secretion by means of tear film fluorophotometry. METHODS: 10 defined concentrations of sodium fluorescein were given in an artificial chamber and measured by the Fluorotron Master (Coherent Radiation Inc). A calibration line was established and the calibration equation was programmed into the Fluorotron Master computer software. In 28 patients (56 eyes) with dry eye symptoms and 15 volunteers (30 eyes) tear volume and tear secretion were then measured directly without taking a tear sample, using the new technique. RESULTS: The values obtained by the Fluorotron Master measuring 10 defined fluorescein concentrations within an artificial chamber are approximately 100 times lower than the actual concentrations. The calibration line led to a calibration equation: y = 36 + 0.01 x X. The mean tear secretion in 56 eyes of patients with dry eye symptoms was 2.48 microl/min, compared to 3.4 microl/min in healthy volunteers. The difference was statistically significant. Average tear volume was 7.0 microl in patients and 7.2 microl in healthy volunteers with no statistically significant difference. CONCLUSION: The method developed is a simple and reliable non-touch technique without the need for taking a tear sample, which makes the examination faster and more comfortable for the patient.

A new technique for tear film fluorophotometry. Publishing Authors By Initials

For similar fluids and secretions: bodily secretions: tears research abstracts see: fluids and secretions: bodily secretions: tears research

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A new technique for tear film fluorophotometry. Journal Published:

PUBLICATION TYPE: Letter

Journal: The British journal of ophthalmology

VOLUME: 86

Page Numbers: 616-9

Journal Abbreviation: Br J Ophthalmol

ISSN: 0007-1161

DAY: 28

MONTH: Jun

YEAR: 2002

A new technique for tear film fluorophotometry. Information

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LANGUAGE: eng

NlmUniqueID: 421041

A new technique for tear film fluorophotometry. Keywords Mesh Terms:

KEYWORDS: Tears

MESH TERMS: secretion

Chemical & Substance for Abstract: A new technique for tear film fluorophotometry. Information

Substance Name: Fluorescein

Registry Number: 2321-07-5

Grant and Affiliation Information for A new technique for tear film fluorophotometry.

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Country: England

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MEDLINETA: Br J Ophthalmol

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