A New Leishmanicidal Saponin from Brunfelsia grandiflora.

A New Leishmanicidal Saponin from Brunfelsia grandiflora. Research Abstract Details 

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A New Leishmanicidal Saponin from Brunfelsia grandiflora. Abstract Text:

Hiroyuki Fuchino,Setsuko Sekita,Kanami Mori,Nobuo Kawahara,Motoyoshi Satake,Fumiyuki Kiuchi,Hiroyuki Fuchino,Setsuko Sekita,Kanami Mori,Nobuo Kawahara,Motoyoshi Satake,Fumiyuki Kiuchi,Hiroyuki Fuchino,Setsuko Sekita,Kanami Mori,Nobuo Kawahara,Motoyoshi Satake,Fumiyuki Kiuchi,Hiroyuki Fuchino,Setsuko Sekita,Kanami Mori,Nobuo Kawahara,Motoyoshi Satake,Fumiyuki Kiuchi,

A new furostan-type saponin (1) was isolated from the methanolic extract of Brunfelsia grandiflora leaves, together with four known compounds. The chemical structure of 1 was determined by spectroscopic analysis and chemical reaction to be 26-O-beta-D-glucopyranosyl 22alpha-methoxyfurost-3beta,26-diol 3-O-beta-D-xylopyranosyl(1-->3)-{beta-D-glucopyranosyl(1-->2)}-beta-D-glucopyranosyl(1-->4)-beta-D-glucopyranoside. Compound 1 showed potent leishmanicidal activity in vitro against Leishmania major.

A New Leishmanicidal Saponin from Brunfelsia grandiflora. Publishing Authors By Initials

H Fuchino,S Sekita,K Mori,N Kawahara,M Satake,F Kiuchi,H Fuchino,S Sekita,K Mori,N Kawahara,M Satake,F Kiuchi,H Fuchino,S Sekita,K Mori,N Kawahara,M Satake,F Kiuchi,H Fuchino,S Sekita,K Mori,N Kawahara,M Satake,F Kiuchi,

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A New Leishmanicidal Saponin from Brunfelsia grandiflora. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Chemical & pharmaceutical bulletin

VOLUME: 56

Page Numbers: 93-6

Journal Abbreviation: Chem. Pharm. Bull.

ISSN: 0009-2363

DAY: 7

MONTH: Jan

YEAR: 2008

A New Leishmanicidal Saponin from Brunfelsia grandiflora. Information

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LANGUAGE: eng

NlmUniqueID: 377775

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AFFILIATION: Research Center for Medicinal Plant Resources, National Institute of Biomedical Innovation.

Country: Japan

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MEDLINETA: Chem Pharm Bull (Tokyo)

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