A mixture model approach to the mapping of QTL controlling endosperm traits with bulked samples.

A mixture model approach to the mapping of QTL controlling endosperm traits with bulked samples. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

A mixture model approach to the mapping of QTL controlling endosperm traits with bulked samples. Abstract Text:

Xuefeng Wang,Zhiqiu Hu,Wei Wang,Yuling Li,Yuan-Ming Zhang,Chenwu Xu,Xuefeng Wang,Zhiqiu Hu,Wei Wang,Yuling Li,Yuan-Ming Zhang,Chenwu Xu,

Endosperm traits are of triploid inheritance and have become a focus of breeding effort for their close relations with the grain quality. Current methods for mapping quantitative trait loci (QTL) underlying endosperm traits are restricted to the use of the phenotypes of single grain samples as input data set, which are often not available in practice due to the small size of the cereal seeds. This paper proposed a statistical model for one specially tailored mapping strategy, where the marker genotypes are obtained from the maternal plants in the segregation population and the phenotypic responses are replaced by the trait means of composite endosperm samples pooled from each plant. It should therefore be more practical and have wide applicability in mapping endosperm traits. The method was implemented by fitting the phenotypic means of endosperms into a Gaussian mixture model. Both the exact and approximate Expectation-Maximization algorithms were proposed to estimate the model parameters. The presence of the QTL was determined by likelihood ratio test statistics. Statistical power and other properties of the new method were investigated and compared to the current single-seed method under a variety of scenarios through simulation studies. The simulations suggest a reasonable sample size should be used to ensure reliable results. The proposed method was also applied to a simulated genome data for further evaluation. As an illustration, a real data of maize was analyzed to find the loci responsible for the popping expansion volume.

A mixture model approach to the mapping of QTL controlling endosperm traits with bulked samples. Publishing Authors By Initials

X Wang,Z Hu,W Wang,Y Li,YM Zhang,C Xu,X Wang,Z Hu,W Wang,Y Li,YM Zhang,C Xu,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

A mixture model approach to the mapping of QTL controlling endosperm traits with bulked samples. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Genetica

VOLUME: 132

Page Numbers: 59-70

Journal Abbreviation: Genetica

ISSN: 0016-6707

DAY: 11

MONTH: 04

YEAR: 2007

A mixture model approach to the mapping of QTL controlling endosperm traits with bulked samples. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 370740

A mixture model approach to the mapping of QTL controlling endosperm traits with bulked samples. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: A mixture model approach to the mapping of QTL controlling endosperm traits with bulked samples. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for A mixture model approach to the mapping of QTL controlling endosperm traits with bulked samples.

AFFILIATION: Jiangsu Provincial Key Laboratory of Crop Genetics and Physiology; Key Laboratory of Plant Functional Genomics of Ministry of Education, Yangzhou University, Yangzhou, 225009, China, qtls@yzu.edu.cn.

Country: Netherlands

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Genetica

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

A mixture model approach to the mapping of QTL controlling endosperm traits with bulked samples Related Publications

• Effects of selenium and iodine on the expression of c-fos and c-jun mRNA and their proteins in cultured rat hippocampus neurons.
• Expression of caltrin in the baculovirus system and its purification in high yield and purity by cobalt (II) affinity chromatography.
• Recombinant human interleukin-10 inhibits proliferation of vascular smooth muscle cells stimulated by advanced glycation end products and neointima hyperplasia after carotid injury in the rat.
• [Analysis of the mutations of BRCA1 in 9 familiar breast cancer patients]
• [Application of the interaction models between the polymorphism(s) of metabolic gene(s) and environmental exposure]
• [Arginine vasopressin-induced nitric oxide content changes in cultured cardiac fibroblasts and its relation to nuclear factor-kappaB]
• [Changes in the activity of platelet L-arginine/nitric oxide pathway in hypercholesterolemia patients]
• [Clinical significance of changes in insulin resistance and secretion in multiple organ dysfunction syndrome patients complicated by trauma and hemorrhage]
• [Cloning and sequencing of the genes coding for the histidine-rich protein II of Plasmodium falciparum]
• [Contrast agents in magnetic resonance imaging: development and problems]
• [Differentially expressed genes associated with cold acclimation]
• [Effects of embryonic neural stem cells and glial cell line-derived neurotrophic factor in the repair of spinal cord injury]
• [Effects of ulinastatin on interleukin-8 during one-lung ventilation in surgery]
• [Isolation and cultivation of neural stem cells from the embryonic rat brain and spinal cord]
• [Mechanism of modulation of synaptic efficacy by stress and learning]
• [Opinion on hydatidosis control by immuno-prophylaxis]
• [Oral mucosa graft combined with a local turn-over flap for urethral reconstruction in various hypospadias]
• [Pharmacognostical studies on the roots of Euphorbia prolifera]
• [Pharmacological comparison between virosecurinine and securinine]
• [Phenotyping and genotyping studies in a family with the compound heterozygosity for a deletional delta beta-thalassemia and a beta-thalassemia]
• [Properties of whole-cell potassium currents in mechanically dissociated Drosophila larval central neurons]
• [Rapid diagnosis of non-deletion alpha-thalassemias by reverse dot blot]
• [Retrospective analysis of effectiveness of tonsillar squamous cell carcinoma: report of 108 cases]
• [Significance of hRad17 mRNA expression in human gastric cancer]
• [Study of functional L1 retrotransposon in human type 2 diabetes susceptibility loci]
• [Study on diarrhea disease and Escherichia coli strains harboring HPI pathogenicity island of Yersinia enterolitica in Shandong province]
• [The experimental study of transfected sFlt-Ig gene on K562 leukemia cell growth in nude mice]
• [The influence of postburn administration of rhGH on the host inflammatory response]
• [The transplantation of latissimus dorsi flap of the base of T shape artery with the pedicle of the thoracodorsal artery]
• [Tissue-specific expression of Na(+)-H(+) exchanger isoforms at two developmental stages of human fetus]