[A Long Survival Case of Advanced Colon Cancer with Lung Metastasis and Cancerous Pleuritis Responding to CPT-11 and S-1 Combination Therapy.]

[A Long Survival Case of Advanced Colon Cancer with Lung Metastasis and Cancerous Pleuritis Responding to CPT-11 and S-1 Combination Therapy.] Research Abstract Details 

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[A Long Survival Case of Advanced Colon Cancer with Lung Metastasis and Cancerous Pleuritis Responding to CPT-11 and S-1 Combination Therapy.] Abstract Text:

Tetsuro Matsuda,Satoru Shikata,

A 71-year-old man underwent right hemicolectomy for an ascending colon cancer (stageII, Cur A) in September 2001. Adjuvant chemotherapy with tegafur/uracil was performed, but CT scans and FDG-PET, conducted in May 2003, revealed cancerous pleuritis and lung metastasis. Although 2 courses of the chemotherapy with LV+5-FU (RPMI regimen) were completed, progressive disease was confirmed. Therefore, the chemotherapy with CPT-11 (100 mg/ day; day 1, 15)+S-1 (100 mg/day; day 1-21) was started in May 2004. After completion of 6 courses, CT scan showed a partial response. Only grade 2 vomiting was noted as an adverse reaction to the treatment, however, the patient has been managed on an outpatient basis for the last 3 years with good QOL and the cancer under control. This case suggests that this combination therapy can be expected to be highly effective as a safe approach for continuously maintaining the QOL of patients with advanced or recurrent colorectal cancer.

[A Long Survival Case of Advanced Colon Cancer with Lung Metastasis and Cancerous Pleuritis Responding to CPT-11 and S-1 Combination Therapy.] Publishing Authors By Initials

T Matsuda,S Shikata,

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[A Long Survival Case of Advanced Colon Cancer with Lung Metastasis and Cancerous Pleuritis Responding to CPT-11 and S-1 Combination Therapy.] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Gan to kagaku ryoho. Cancer & chemotherapy

VOLUME: 35

Page Numbers: 511-3

Journal Abbreviation: Gan To Kagaku Ryoho

ISSN: 0385-0684

DAY: 18

MONTH: Mar

YEAR: 2008

[A Long Survival Case of Advanced Colon Cancer with Lung Metastasis and Cancerous Pleuritis Responding to CPT-11 and S-1 Combination Therapy.] Information

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LANGUAGE: jpn

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AFFILIATION: Dept. of Surgery, Soseikai General Hospital.

Country: Japan

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MEDLINETA: Gan To Kagaku Ryoho

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