A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli.

A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli. Research Abstract Details 

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A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli. Abstract Text:

mazEF is a toxin-antitoxin module located on many bacterial chromosomes, including those of pathogens. Here, we report that Escherichia coli mazEF-mediated cell death is a population phenomenon requiring a quorum-sensing molecule that we call the extracellular death factor (EDF). Structural analysis revealed that EDF is a linear pentapeptide, Asn-Asn-Trp-Asn-Asn. Each of the five amino acids of EDF is important for its activity.

A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli. Publishing Authors By Initials

For similar biological phenomena, cell phenomena, and immunity: cell physiology: cell communication: quorum sensing research abstracts see: biological phenomena, cell phenomena, and immunity: cell physiology: cell communication: quorum sensing research

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A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Science (New York, N.Y.)

VOLUME: 318

Page Numbers: 652-5

Journal Abbreviation: Science

ISSN: 1095-9203

DAY: 26

MONTH: Oct

YEAR: 2007

A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli. Information

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LANGUAGE: eng

NlmUniqueID: 404511

A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli. Keywords Mesh Terms:

KEYWORDS: Quorum Sensing

MESH TERMS: metabolism

Chemical & Substance for Abstract: A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli. Information

Substance Name: Aspartate-Ammonia Ligase

Registry Number: EC 6.3.1.1

Grant and Affiliation Information for A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli.

AFFILIATION: Department of Molecular Biology, Hebrew University-Hadassah Medical School, Jerusalem 91120, Israel.

Country: United States

AGENCY: United States NIGMS

GRANT: GM069509

ACRONYM: GM

MEDLINETA: Science

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A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli Related Publications

• A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli.
• The extracellular death factor: physiological and genetic factors influencing its production and response in Escherichia coli.