A kinetic study of the endolymphatic sac epithelial cells.

A kinetic study of the endolymphatic sac epithelial cells. Research Abstract Details 

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A kinetic study of the endolymphatic sac epithelial cells. Abstract Text:

M Takahashi,T Unno,

The kinetics of S-phase (the period of DNA synthesis) cells in the endolymphatic sac (ES) was investigated by immunohistochemical methods. A monoclonal antibody against 5 bromo 2'-deoxyuridine (BrdUrd) was used. After administration of BrdUrd i.p., guinea pigs were sacrificed with acid formalin at designated survival times until 28 days, and the decalcified temporal bones were examined immunohistochemically. After survival for 30 min, scattered cells labelled with an anti-BrdUrd antibody were detected within the ES, whereas they were not found any other part of the inner ear. Labelled cells were observed more frequently in the rugose portion than in the other portion of the ES. At 3 days after BrdUrd labelling, increased numbers of labelled cells were detected. Labelled mitoses could be observed in the epithelium after long survival times. Our results show that the epithelial cells of the ES in adult animals turn over in the steady-state.

A kinetic study of the endolymphatic sac epithelial cells. Publishing Authors By Initials

M Takahashi,T Unno,

For similar natural sciences: time: time factors research abstracts see: natural sciences: time: time factors research

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A kinetic study of the endolymphatic sac epithelial cells. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Acta oto-laryngologica. Supplementum

VOLUME: 519

Page Numbers: 244-7

Journal Abbreviation:

ISSN: 0365-5237

DAY: 13

MONTH: 02

YEAR: 1995

A kinetic study of the endolymphatic sac epithelial cells. Information

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LANGUAGE: eng

NlmUniqueID: 370355

A kinetic study of the endolymphatic sac epithelial cells. Keywords Mesh Terms:

KEYWORDS: Time Factors

MESH TERMS: cytology

Chemical & Substance for Abstract: A kinetic study of the endolymphatic sac epithelial cells. Information

Substance Name: Bromodeoxyuridine

Registry Number: 59-14-3

Grant and Affiliation Information for A kinetic study of the endolymphatic sac epithelial cells.

AFFILIATION: Department of Otolaryngology, Asahikawa Medical School, Hokkaido, Japan.

Country: NORWAY

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MEDLINETA: Acta Otolaryngol Suppl

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