A histologic review of 27 patients with lichen planopilaris.

A histologic review of 27 patients with lichen planopilaris. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

A histologic review of 27 patients with lichen planopilaris. Abstract Text:

BACKGROUND: Lichen planopilaris (LPP) is a potential trichologic emergency that can result in permanent scarring alopecia. Histopathology is a key component of the diagnostic work-up. OBJECTIVE: To identify the key histologic features that characterize LPP in order to facilitate diagnosis, ultimately leading to improved patient outcomes. METHODS: Scalp biopsy specimens from 27 confirmed cases of LPP were reviewed in a blinded fashion to determine diagnostically helpful histologic features. RESULTS: Absence of arrector pili muscles and sebaceous glands, a perivascular and perifollicular lymphocytic infiltrate in the reticular dermis and mucinous perifollicular fibroplasia within the upper dermis with absence of interfollicular mucin, and superficial perifollicular wedge-shaped scarring were characterizing features. LIMITATIONS: Sample size was limited, given that biopsy specimens were taken from lesions at varying stages of evolution and findings vary with disease stage. CONCLUSIONS: This study confirms many previously reported histologic features and highlights new characterizing features of mucinous perifollicular fibroplasia.

A histologic review of 27 patients with lichen planopilaris. Publishing Authors By Initials

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

A histologic review of 27 patients with lichen planopilaris. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of the American Academy of Dermatology

VOLUME: 59

Page Numbers: 91-8

Journal Abbreviation: J. Am. Acad. Dermatol.

ISSN: 1097-6787

DAY: 23

MONTH: Jul

YEAR: 2008

A histologic review of 27 patients with lichen planopilaris. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 7907132

A histologic review of 27 patients with lichen planopilaris. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: A histologic review of 27 patients with lichen planopilaris. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for A histologic review of 27 patients with lichen planopilaris.

AFFILIATION: Faculty of Medicine, North Eastern Ohio Universities Colleges of Medicine and Pharmacy, Rootstown, Ohio.

Country: United States

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: J Am Acad Dermatol

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

A histologic review of 27 patients with lichen planopilaris Related Publications

• A histologic review of 27 patients with lichen planopilaris.
• Callused feet, thick nails, and white tongue. Pachyonychia congenita.
• Chronic alopecia. Trichotillomania.
• Cicatricial alopecia: classification and histopathology.
• Differences in biopsy techniques of actinic keratoses by plastic surgeons and dermatologists: a histologically controlled pilot study.
• Epidermolysis bullosa acquisita. Report of three cases and review of all published cases.
• Metastatic transitional cell carcinoma mimicking zoster sine herpete.
• Relapsing polychondritis with positive direct immunofluorescence.
• The clinical evaluation of hirsutism.
• Tumor cell characterization of histiocytic medullary reticulosis.