A Dynamical Model on the Network of p53-Mdm2 Feedback Loop Regulated by p14/19ARF.

A Dynamical Model on the Network of p53-Mdm2 Feedback Loop Regulated by p14/19ARF. Research Abstract Details 

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A Dynamical Model on the Network of p53-Mdm2 Feedback Loop Regulated by p14/19ARF. Abstract Text:

Hui Liu,Ying-Rong Han,Yong Zhan,Ya-Fei Chen,Yu-Hong Zhang,Hui Yu,Tong-Jun Zhao,Yi-Zhong Zhuo,

Base on new experimental results, we give a dynamical model to study the dynamical mechanism of the negative feedback loop composed of p53 and Mdm2 proteins regulated by p14/19ARF. The oscillatory behaviors for the activities of p53 and Mdm2 proteins regulated by p14/19ARF in individual of cells are described in our dynamical model. The results help us build a basal network about oscillatory behaviors among p53, Mdm2 and P14/19ARF. The dynamical model and its numerical results will help us understand the oscillatory behavior among other network of different proteins.

A Dynamical Model on the Network of p53-Mdm2 Feedback Loop Regulated by p14/19ARF. Publishing Authors By Initials

H Liu,YR Han,Y Zhan,YF Chen,YH Zhang,H Yu,TJ Zhao,YZ Zhuo,

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A Dynamical Model on the Network of p53-Mdm2 Feedback Loop Regulated by p14/19ARF. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Conference proceedings : ... Annual International

VOLUME: 1

Page Numbers: 4235-8

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ISSN: 1557-170X

DAY: 16

MONTH: 11

YEAR: 2007

A Dynamical Model on the Network of p53-Mdm2 Feedback Loop Regulated by p14/19ARF. Information

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LANGUAGE: eng

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AFFILIATION: School of Science, Hebei University of Technology, Tianjin, China. phone: +86-22-60204802; e-mail: lhcell@163.com.

Country: United States

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