A developmental study of the structural integrity of white matter in autism.

A developmental study of the structural integrity of white matter in autism. Research Abstract Details 

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A developmental study of the structural integrity of white matter in autism. Abstract Text:

Timothy A Keller,Rajesh K Kana,Marcel Adam Just,

Diffusion tensor imaging was used to examine developmental changes in the organization of white matter in a large sample of male participants with autism and controls between the ages of 10 and 35 years. Participants with autism had lower fractional anisotropy in areas within and near the corpus callosum and in the right retrolenticular portion of the internal capsule. Only one area, in the posterior limb of the right internal capsule, showed an interaction between age and group. The findings suggest that reductions in the structural integrity of white matter in autism persist into adulthood. These reductions may underlie the behavioral pattern observed in autism, as well as findings of reduced functional connectivity in functional magnetic resonance imaging signal between activating cortical areas.

A developmental study of the structural integrity of white matter in autism. Publishing Authors By Initials

TA Keller,RK Kana,MA Just,

For similar male research abstracts see: male research

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A developmental study of the structural integrity of white matter in autism. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Neuroreport

VOLUME: 18

Page Numbers: 23-7

Journal Abbreviation: Neuroreport

ISSN: 0959-4965

DAY: 8

MONTH: Jan

YEAR: 2007

A developmental study of the structural integrity of white matter in autism. Information

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LANGUAGE: eng

NlmUniqueID: 9100935

A developmental study of the structural integrity of white matter in autism. Keywords Mesh Terms:

KEYWORDS: Male

MESH TERMS: pathology

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Grant and Affiliation Information for A developmental study of the structural integrity of white matter in autism.

AFFILIATION: Center for Cognitive Brain Imaging, Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania, USA. tk37@andrew.cmu.edu

Country: England

AGENCY: United States NICHD

GRANT: HD35469

ACRONYM: HD

MEDLINETA: Neuroreport

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