A decade of surprises for tRNA nuclear-cytoplasmic dynamics.

A decade of surprises for tRNA nuclear-cytoplasmic dynamics. Research Abstract Details 

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A decade of surprises for tRNA nuclear-cytoplasmic dynamics. Abstract Text:

The biosynthesis of tRNA was previously thought to occur solely in the nucleus, with tRNA functioning only in the cytoplasm of eukaryotic cells. However, recent publications have reported that pre-tRNA splicing can occur in the cytoplasm, that aminoacylation can occur in the nucleus and that tRNA can travel in a retrograde direction from the cytoplasm to the nucleus. Moreover, the subcellular distribution of tRNA seems to serve unanticipated functions in diverse processes, including response to nutrient availability, DNA repair and HIV replication.

A decade of surprises for tRNA nuclear-cytoplasmic dynamics. Publishing Authors By Initials

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A decade of surprises for tRNA nuclear-cytoplasmic dynamics. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Trends in cell biology

VOLUME: 18

Page Numbers: 98-104

Journal Abbreviation: Trends Cell Biol.

ISSN: 0962-8924

DAY: 11

MONTH: 02

YEAR: 2008

A decade of surprises for tRNA nuclear-cytoplasmic dynamics. Information

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LANGUAGE: eng

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Grant and Affiliation Information for A decade of surprises for tRNA nuclear-cytoplasmic dynamics.

AFFILIATION: Department of Molecular Genetics, Ohio State University, 484 West 12th Avenue, Room Riffe 800, Columbus, OH 43210, USA. hopper.64@osu.edu

Country: England

AGENCY: United States NIGMS

GRANT: GM27930

ACRONYM: GM

MEDLINETA: Trends Cell Biol

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