A comparison of proximity and land use regression traffic exposure models and wheezing in infants.

A comparison of proximity and land use regression traffic exposure models and wheezing in infants. Research Abstract Details 

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A comparison of proximity and land use regression traffic exposure models and wheezing in infants. Abstract Text:

Patrick H Ryan,Grace K Lemasters,Pratim Biswas,Linda Levin,Shaohua Hu,Mark Lindsey,David I Bernstein,James Lockey,Manuel Villareal,Gurjit K Khurana Hershey,Sergey A Grinshpun,

BACKGROUND: We previously reported an association between infant wheezing and residence < 100 m from stop-and-go bus and truck traffic. The use of a proximity model, however, may lead to exposure misclassification. OBJECTIVE: Results obtained from a land use regression (LUR) model of exposure to truck and bus traffic are compared with those obtained with a proximity model. The estimates derived from the LUR model were then related to infant wheezing. METHODS: We derived a marker of diesel combustion--elemental carbon attributable to traffic sources (ECAT)--from ambient monitoring results of particulate matter with aerodynamic diameter < 2.5 microm. We developed a multiple regression model with ECAT as the outcome variable. Variables included in the model were locations of major roads, bus routes, truck traffic count, and elevation. Model parameter estimates were applied to estimate individual ECAT levels at infants' homes. RESULTS: The levels of estimated ECAT at the monitoring stations ranged from 0.20 to 1.02 microg/m(3). A LUR model of exposure with a coefficient of determination (R(2)) of 0.75 was applied to infants' homes. The mean (+/- SD) ambient exposure of ECAT for infants previously categorized as unexposed, exposed to stop-and-go traffic, or exposed to moving traffic was 0.32 +/- 0.06, 0.42 +/- 0.14, and 0.49 +/- 0.14 microg/m(3), respectively. Levels of ECAT from 0.30 to 0.90 mug/m(3) were significantly associated with infant wheezing. CONCLUSIONS: The LUR model resulted in a range of ECAT individually derived for all infants' homes that may reduce the exposure misclassification that can arise from a proximity model.

A comparison of proximity and land use regression traffic exposure models and wheezing in infants. Publishing Authors By Initials

PH Ryan,GK Lemasters,P Biswas,L Levin,S Hu,M Lindsey,DI Bernstein,J Lockey,M Villareal,GK Khurana Hershey,SA Grinshpun,

For similar complex mixtures: vehicle emissions research abstracts see: complex mixtures: vehicle emissions research

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A comparison of proximity and land use regression traffic exposure models and wheezing in infants. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Environmental health perspectives

VOLUME: 115

Page Numbers: 278-84

Journal Abbreviation: Environ. Health Perspect.

ISSN: 0091-6765

DAY: 30

MONTH: 10

YEAR: 2006

A comparison of proximity and land use regression traffic exposure models and wheezing in infants. Information

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LANGUAGE: eng

NlmUniqueID: 330411

A comparison of proximity and land use regression traffic exposure models and wheezing in infants. Keywords Mesh Terms:

KEYWORDS: Vehicle Emissions

MESH TERMS: analysis

Chemical & Substance for Abstract: A comparison of proximity and land use regression traffic exposure models and wheezing in infants. Information

Substance Name: Carbon

Registry Number: 7440-44-0

Grant and Affiliation Information for A comparison of proximity and land use regression traffic exposure models and wheezing in infants.

AFFILIATION: Department of Environmental Health, University of Cincinnati Medical Center, Cincinnati, Ohio 45267, USA. patrick.ryan@uc.edu

Country: United States

AGENCY: United States NIEHS

GRANT: ES11170

ACRONYM: ES

MEDLINETA: Environ Health Perspect

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