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A clinical comparison of melperone and placebo in schizophrenic women on a milieu therapeutic ward.

A clinical comparison of melperone and placebo in schizophrenic women on a milieu therapeutic ward. Research Abstract Details 

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  • A clinical comparison of melperone and placebo in schizophrenic women on a milieu therapeutic ward. Abstract Text:

    c härnrydC Härnryd,l bjerkenstedtL Bjerkenstedt,b gullbergB Gullberg,

    Twenty schizophrenic women participated in a double-blind comparison of melperone (300 mg daily) and placebo lasting 4 weeks. All the patients received milieu treatment. Two patients in the melperone and four in the placebo group were removed from the study due to unsatisfactory therapeutic response. In the melperone group, there were significant reductions in psychotic morbidity. In the placebo group, there were occasional significant reductions of psychotic morbidity during but not at the end of treatment. The melperone-treated patients exhibited significantly lower morbidity scores than the placebo group after treatment for two and four weeks. The melperone group demonstrated significantly more adverse reactions than placebo-treated patients at the end of the study. The results support the view that melperone exerts an antipsychotic effect. The study is consistent with the opinion that milieu therapy should be combined with neuroleptics to achieve an optimal result in the treatment of an acute phase of schizophrenia.

    A clinical comparison of melperone and placebo in schizophrenic women on a milieu therapeutic ward. Publishing Authors By Initials

    c härnrydC Härnryd,l bjerkenstedtL Bjerkenstedt,b gullbergB Gullberg,

    For similar behavioral disciplines and activities: psychotherapy: socioenvironmental therapy: milieu therapy: therapeutic community research abstracts see: behavioral disciplines and activities: psychotherapy: socioenvironmental therapy: milieu therapy: therapeutic community research

    PUBMED ID PMID:

    MEDLINE DATE:

    A clinical comparison of melperone and placebo in schizophrenic women on a milieu therapeutic ward. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Acta psychiatrica Scandinavica. Supplementum

    VOLUME: 352

    Page Numbers: 40-7

    Journal Abbreviation:

    ISSN: 0065-1591

    DAY: 15

    MONTH: 02

    YEAR: 1989

    A clinical comparison of melperone and placebo in schizophrenic women on a milieu therapeutic ward. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 370365

    A clinical comparison of melperone and placebo in schizophrenic women on a milieu therapeutic ward. Keywords Mesh Terms:

    KEYWORDS: Therapeutic Community

    MESH TERMS: drug therapy

    Chemical & Substance for Abstract: A clinical comparison of melperone and placebo in schizophrenic women on a milieu therapeutic ward. Information

    Substance Name: metylperon

    Registry Number: 3575-80-2

    Grant and Affiliation Information for A clinical comparison of melperone and placebo in schizophrenic women on a milieu therapeutic ward.

    AFFILIATION: Department of Psychiatry and Psychology, Karolinska Institute, Sweden.

    Country: DENMARK

    DENMARK Research PublicationDENMARK Research Publication

    AGENCY:

    GRANT:

    ACRONYM:

    MEDLINETA: Acta Psychiatr Scand Suppl

    REFSOURCE:

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