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A cell-binding, immunoglobulin-like protein from human plasma. II. Cell-binding activity.

A cell-binding, immunoglobulin-like protein from human plasma. II. Cell-binding activity. Research Abstract Details 

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  • A cell-binding, immunoglobulin-like protein from human plasma. II. Cell-binding activity. Abstract Text:

    h fukamizuH Fukamizu,k ohoriK Ohori,y naitoY Naito,k horiuchiK Horiuchi,d fujimotoD Fujimoto,

    Cell adhesion to plastic surfaces coated with a new high-molecular-mass immunoglobulin-like protein from normal human plasma was studied. Mouse subdermal fibroblasts, hamster kidney cells, human umbilical vein endothelial cells, and human skin fibroblasts were found to become attached to the surface, but cancer cells derived from human stomach cancer and human breast cancer did not. The appearance of the attached cells differed from that of cells attached to surfaces coated with fibronectin or concanavalin A. The cell adhesion to the surfaces coated with the protein was inhibited by goat anti-human IgM. Furthermore, the binding of the protein to the cell surfaces was demonstrated by the indirect immunofluorescence method. It is concluded that this protein is a new cell-binding protein.

    A cell-binding, immunoglobulin-like protein from human plasma. II. Cell-binding activity. Publishing Authors By Initials

    h fukamizuH Fukamizu,k ohoriK Ohori,y naitoY Naito,k horiuchiK Horiuchi,d fujimotoD Fujimoto,

    For similar biochemical phenomena, metabolism, and nutrition: biochemical phenomena: protein binding research abstracts see: biochemical phenomena, metabolism, and nutrition: biochemical phenomena: protein binding research

    PUBMED ID PMID:

    MEDLINE DATE:

    A cell-binding, immunoglobulin-like protein from human plasma. II. Cell-binding activity. Journal Published:

    PUBLICATION TYPE: Research Support, Non-U.S. Gov

    Journal: Journal of biochemistry

    VOLUME: 100

    Page Numbers: 843-8

    Journal Abbreviation: J. Biochem.

    ISSN: 0021-924X

    DAY: 19

    MONTH: Oct

    YEAR: 1986

    A cell-binding, immunoglobulin-like protein from human plasma. II. Cell-binding activity. Information

    Number of References:

    LANGUAGE: eng

    NlmUniqueID: 376600

    A cell-binding, immunoglobulin-like protein from human plasma. II. Cell-binding activity. Keywords Mesh Terms:

    KEYWORDS: Protein Binding

    MESH TERMS: metabolism

    Chemical & Substance for Abstract: A cell-binding, immunoglobulin-like protein from human plasma. II. Cell-binding activity. Information

    Substance Name: cell-binding immunoglobulin-like protein

    Registry Number: 0

    Grant and Affiliation Information for A cell-binding, immunoglobulin-like protein from human plasma. II. Cell-binding activity.

    AFFILIATION:

    Country: JAPAN

    JAPAN Research PublicationJAPAN Research Publication

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    GRANT:

    ACRONYM:

    MEDLINETA: J Biochem

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