A cell-binding, immunoglobulin-like protein from human plasma. I. Isolation and subunit structure.

A cell-binding, immunoglobulin-like protein from human plasma. I. Isolation and subunit structure. Research Abstract Details 

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A cell-binding, immunoglobulin-like protein from human plasma. I. Isolation and subunit structure. Abstract Text:

K Ohori,H Fukamizu,K Matsushita,K Horiuchi,D Fujimoto,

A protein having Mr of more than 900K (900,000) was isolated by chromatography on a column of Sepharose 4B coupled with solubilized elastin, followed by sucrose density gradient centrifugation. The protein is composed of several disulfide-linked subunits. SDS-polyacrylamide gel electrophoresis and immunoblotting indicated that two of the subunits are identical with the heavy chains of IgM and IgG, and one is immunologically related to the heavy chain of IgA. The results suggested that this protein is a new protein that belongs to the category of, or is closely related to, the immunoglobulins. As described in the succeeding paper, it has cell-binding activity (Fukamizu et al. (1986) J. Biochem. 100, 843-848). We tentatively refer to this protein as "cell-binding immunoglobulin-like protein (CIP)."

A cell-binding, immunoglobulin-like protein from human plasma. I. Isolation and subunit structure. Publishing Authors By Initials

K Ohori,H Fukamizu,K Matsushita,K Horiuchi,D Fujimoto,

For similar biochemical phenomena, metabolism, and nutrition: biochemical phenomena: protein binding research abstracts see: biochemical phenomena, metabolism, and nutrition: biochemical phenomena: protein binding research

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A cell-binding, immunoglobulin-like protein from human plasma. I. Isolation and subunit structure. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Journal of biochemistry

VOLUME: 100

Page Numbers: 837-42

Journal Abbreviation: J. Biochem.

ISSN: 0021-924X

DAY: 19

MONTH: Oct

YEAR: 1986

A cell-binding, immunoglobulin-like protein from human plasma. I. Isolation and subunit structure. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 376600

A cell-binding, immunoglobulin-like protein from human plasma. I. Isolation and subunit structure. Keywords Mesh Terms:

KEYWORDS: Protein Binding

MESH TERMS: metabolism

Chemical & Substance for Abstract: A cell-binding, immunoglobulin-like protein from human plasma. I. Isolation and subunit structure. Information

Substance Name: Chymotrypsin

Registry Number: EC 3.4.21.1

Grant and Affiliation Information for A cell-binding, immunoglobulin-like protein from human plasma. I. Isolation and subunit structure.

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Country: JAPAN

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MEDLINETA: J Biochem

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