A case report of thrombotic thrombocytopenic purpura and severe acute renal failure post non-myeloablative allogeneic peripheral blood stem cell transplantation treated with plasma exchange and hemodialysis.

A case report of thrombotic thrombocytopenic purpura and severe acute renal failure post non-myeloablative allogeneic peripheral blood stem cell transplantation treated with plasma exchange and hemodialysis. Research Abstract Details 

Research Abstract Table of Contents

Jump to the:

A case report of thrombotic thrombocytopenic purpura and severe acute renal failure post non-myeloablative allogeneic peripheral blood stem cell transplantation treated with plasma exchange and hemodialysis. Abstract Text:

Yujiro Kida,Toshihide Ishii,Minoru Ando,Eiichiro Kanda,Hitoe Suzuki,Aiko Kida,Takuya Yamashita,Hisashi Sakamaki,Hiroshi Saito,Yujiro Kida,Toshihide Ishii,Minoru Ando,Eiichiro Kanda,Hitoe Suzuki,Aiko Kida,Takuya Yamashita,Hisashi Sakamaki,Hiroshi Saito,

A 59-year-old-woman received related non-myeloablative allogeneic peripheral blood stem cell transplantation (PBSCT) subsequent to autologous PBSCT in our hospital five years after she was diagnosed as oligo-secretory myeloma. She was admitted to our hospital because of vomiting and grayish diarrhea 4 months after non-myeloablative allogeneic PBSCT (mini-alloPBSCT). Although her initial symptoms improved after admission, she gradually showed thrombocytopenia, anemia, and oliguria during the 2 weeks after admission. Our diagnosis was thrombotic thrombocytopenic purpura (TTP) and acute renal failure (ARF) secondary to mini-alloPBSCT. After cessation of cyclosporine administration, we began to treat her with plasma exchange (PE) and hemodialysis. During the three and a half months after we started PE, the TTP gradually improved. Although PE had been reported to be ineffective for TTP post bone marrow transplantation, we could finally discontinue PE. In contrast, since her anuria continued, she was managed with hemodialysis. One month after PE was started, her activity of von Willebrand factor-cleaving protease was 41% (normal range, >50%) and the ultrasonographic investigation of both kidneys was normal. She could be discharged after four and a half months hospitalization and lived well as an outpatient for a further two months. She died shortly after readmission from multiple organ failure without the relapse of TTP. The patient's clinical course would suggest that TTP post mini-alloPBSCT could be treated with PE in some cases, despite the development of dialysis-requiring severe ARF being a poor prognostic factor.

A case report of thrombotic thrombocytopenic purpura and severe acute renal failure post non-myeloablative allogeneic peripheral blood stem cell transplantation treated with plasma exchange and hemodialysis. Publishing Authors By Initials

Y Kida,T Ishii,M Ando,E Kanda,H Suzuki,A Kida,T Yamashita,H Sakamaki,H Saito,Y Kida,T Ishii,M Ando,E Kanda,H Suzuki,A Kida,T Yamashita,H Sakamaki,H Saito,

For similar abstracts research abstracts see: abstracts research

PUBMED ID PMID:

MEDLINE DATE:

A case report of thrombotic thrombocytopenic purpura and severe acute renal failure post non-myeloablative allogeneic peripheral blood stem cell transplantation treated with plasma exchange and hemodialysis. Journal Published:

PUBLICATION TYPE: Research Support, Non-U.S. Gov

Journal: Therapeutic apheresis and dialysis : official peer

VOLUME: 11

Page Numbers: 402-6

Journal Abbreviation:

ISSN: 1744-9979

DAY: 11

MONTH: Oct

YEAR: 2007

A case report of thrombotic thrombocytopenic purpura and severe acute renal failure post non-myeloablative allogeneic peripheral blood stem cell transplantation treated with plasma exchange and hemodialysis. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 101181252

A case report of thrombotic thrombocytopenic purpura and severe acute renal failure post non-myeloablative allogeneic peripheral blood stem cell transplantation treated with plasma exchange and hemodialysis. Keywords Mesh Terms:

KEYWORDS:

MESH TERMS:

Chemical & Substance for Abstract: A case report of thrombotic thrombocytopenic purpura and severe acute renal failure post non-myeloablative allogeneic peripheral blood stem cell transplantation treated with plasma exchange and hemodialysis. Information

Substance Name:

Registry Number:

Grant and Affiliation Information for A case report of thrombotic thrombocytopenic purpura and severe acute renal failure post non-myeloablative allogeneic peripheral blood stem cell transplantation treated with plasma exchange and hemodialysis.

AFFILIATION: Department of Internal Medicine, Division of Nephrology, Tokyo Metropolitan Komagome Hospital, Tokyo, Japan. ykida@usc.edu

Country: Australia

AGENCY:

GRANT:

ACRONYM:

MEDLINETA: Ther Apher Dial

REFSOURCE:

DATABASENAME:

ACCESSION NUMBER:

Number Hits: 0

A case report of thrombotic thrombocytopenic purpura and severe acute renal failure post non-myeloablative allogeneic peripheral blood stem cell transplantation treated with plasma exchange and hemodialysis Related Publications

• A case report of thrombotic thrombocytopenic purpura and severe acute renal failure post non-myeloablative allogeneic peripheral blood stem cell transplantation treated with plasma exchange and hemodialysis.
• ANP is cleared much faster than BNP in patients with congestive heart failure.
• Acute carotid arterial occlusion after burr hole surgery for chronic subdural haematoma in moyamoya disease.
• Brownian motion of helical flagella.
• Change in atrial flutter wave morphology-insight into the sources of electrocardiographic variants in common atrial flutter.
• Congenital left ventricular diverticulum in an adult.
• Effects of Methamphetamine on Cortisone Concentration, NK Cell Activity and Mitogen Response of T-lymphocytes in Female Cynomolgus Monkeys.
• Effects of Plastoquinones from the Brown Alga Sargassum micracanthum and a New Chromene Derivative Converted from the Plastoquinones on Acute Gastric Lesions in Rats.
• Effects of gangliosides on ethanol-induced neurodegeneration in the developing mouse brain.
• Electrophysiological properties of the atrium after cardioversion of chronic atrial fibrillation.
• Expression of angiotensin II type I receptor in human cirrhotic livers: Its relation to fibrosis and portal hypertension.
• Identification of novel n-4 series polyunsaturated fatty acids in a deep-sea clam, Calyptogena phaseoliformis.
• Impact of laparoscopic cystectomy on fecundity of infertility patients with ovarian endometrioma.
• Importance of chroman ring and tyrosine phosphorylation in the subtype-specific translocation and activation of diacylglycerol kinase alpha by D-alpha-tocopherol.
• Intramolecular alpha-helix-beta-structure-random coil transition in polypeptides I. Equilibrium case.
• Intramolecular alpha-helix-beta-structure-random coil transition in polypeptides II. Dynamic case.
• Laparoscopy should be strongly considered for women with unexplained infertility.
• Measurement and Analysis of Reflex Responses to Perturbation during Walking-Towards the Realization of Artificial Reflex.
• Olanzapine potentiates neuronal survival and neural stem cell differentiation: regulation of endoplasmic reticulum stress response proteins.
• Periodontal regeneration of transplanted rat teeth subcutaneously after cryopreservation.
• Phenotypic changes associated with exogenous expression of p16INK4a in human glioma cells.
• Prostate-specific antigen cut-off point of 2.5 ng/mL and increasing the number of prostate biopsies results in the detection of curable prostate cancer even in Japanese population.
• Second branchial cleft cyst with "cyst-within-cyst" appearance.
• Spatial distribution of mDLG6 mRNA in embryonic and adult mouse brain.
• Spatiotemporal Analysis of the Molecular Interaction between PICK1 and PKC.
• Sulfonamide derivatives as new potent and selective CB2 cannabinoid receptor agonists.
• The random walk description for isotope exchange in a polypeptide.
• Threshold-like pattern of neuronal activation in the hypothalamus during treadmill running: establishment of a minimum running stress (MRS) rat model.
• [Affected State due to Excessive Occlusal Force.]
• [Repair of bone tissue using rhBMP-2]