[A case of recurrent breast cancer with multiple liver metastases responding to combination therapy of capecitabine and MPA]

[A case of recurrent breast cancer with multiple liver metastases responding to combination therapy of capecitabine and MPA] Research Abstract Details 

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[A case of recurrent breast cancer with multiple liver metastases responding to combination therapy of capecitabine and MPA] Abstract Text:

Kazuya Konishi,Naoto Hasegawa,Makoto Kawabata,Shigeki Abeshima,Tatsunosuke Ichimura,Hiroyuki Kaneko,Tomohide Nakayama,Kazuya Konishi,Naoto Hasegawa,Makoto Kawabata,Shigeki Abeshima,Tatsunosuke Ichimura,Hiroyuki Kaneko,Tomohide Nakayama,

The patient was a 68-year-old woman who underwent left partial mastectomy on February 1999. The stage was T2N1. There were positive for estrogen and progesterone receptors in the tumor. After operation, adjuvant therapy consisting of oral administration of tamoxifen and radiation was performed. On February 2005, she felt dyspnea and right femoral pain. After examinations, she was diagnosed as recurrent breast cancer with pleuritis carcinomatosa and bone metastasis. The patient was treated with oral administration of anastrozole and pamidronate disodium 90 mg intravenously every 4 weeks, radiation of her right femur, and OK-432 injection into the intrapleural cavity. On November 2005, she felt general fatigue and anorexia. CT examination revealed multiple liver metastases. She was treated with oral combination chemoendocrine therapy with capecitabine (2,400 mg/day) and MPA (600 mg/day). After the four courses, multiple liver metastases were remarkably reduced in the CT findings. After twelve courses, the partial response continued. No adverse reactions occurred except for gain in weight of grade 1. It is suggested that this oral combination chemoendocrine therapy may be useful for recurrent breast cancer with consideration for treatment effectiveness and the quality of life of the patient.

[A case of recurrent breast cancer with multiple liver metastases responding to combination therapy of capecitabine and MPA] Publishing Authors By Initials

K Konishi,N Hasegawa,M Kawabata,S Abeshima,T Ichimura,H Kaneko,T Nakayama,K Konishi,N Hasegawa,M Kawabata,S Abeshima,T Ichimura,H Kaneko,T Nakayama,

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[A case of recurrent breast cancer with multiple liver metastases responding to combination therapy of capecitabine and MPA] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Gan to kagaku ryoho. Cancer & chemotherapy

VOLUME: 34

Page Numbers: 1689-91

Journal Abbreviation: Gan To Kagaku Ryoho

ISSN: 0385-0684

DAY: 17

MONTH: Oct

YEAR: 2007

[A case of recurrent breast cancer with multiple liver metastases responding to combination therapy of capecitabine and MPA] Information

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LANGUAGE: jpn

NlmUniqueID: 7810034

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AFFILIATION: Dept. of Surgery, Kushiro City General Hospital.

Country: Japan

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MEDLINETA: Gan To Kagaku Ryoho

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