[A case of loxoprofen sodium-induced eosinophilic pneumonia that occurred ipsilaterally after VATS lobectomy for lung cancer]

[A case of loxoprofen sodium-induced eosinophilic pneumonia that occurred ipsilaterally after VATS lobectomy for lung cancer] Research Abstract Details 

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[A case of loxoprofen sodium-induced eosinophilic pneumonia that occurred ipsilaterally after VATS lobectomy for lung cancer] Abstract Text:

Takehiro Izumo,Mitsuko Kondo,Masahiro Mae,Shigemitsu Onizawa,Naoki Nagara,Tomoko Nozu,Jun Tamaoki,Takamasa Ohnuki,Atsushi Nagai,Takehiro Izumo,Mitsuko Kondo,Masahiro Mae,Shigemitsu Onizawa,Naoki Nagara,Tomoko Nozu,Jun Tamaoki,Takamasa Ohnuki,Atsushi Nagai,

A 76-year-old man was admitted because of dry cough and dyspnea two weeks after VATS lobectomy for lung cancer. Chest radiographs and computed tomography showed interstitial shadows in the only operative lung side. Although antibiotic drugs were given because we believed it to be postoperative pneumonia, abnormal shadows on chest radiographs increased. A bronchoalveolar lavage fluid (BALF) study performed on the 21" day after operation showed that the proportions of eosinophils, basophils and mast cells had increased, and the CD4/CD8 ratio was 4.42. The drug lymphocyte stimulation test for loxoprofen sodium was positive. Based on the clinical course, laboratory data and BALF study, we arrived at a diagnosis of drug-induced pneumonia caused by loxoprofen sodium. Treatment with corticosteroid resulted in marked improvement of the chest radiographs and clinical findings. Drug-induced pneumonia usually occurs bilaterally, but it occurred only on the operative side in this case. Although rare, it is important to recognize that unilateral drug-induced pneumonia is one of the differential diagnose of postoperative pneumonia.

[A case of loxoprofen sodium-induced eosinophilic pneumonia that occurred ipsilaterally after VATS lobectomy for lung cancer] Publishing Authors By Initials

T Izumo,M Kondo,M Mae,S Onizawa,N Nagara,T Nozu,J Tamaoki,T Ohnuki,A Nagai,T Izumo,M Kondo,M Mae,S Onizawa,N Nagara,T Nozu,J Tamaoki,T Ohnuki,A Nagai,

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[A case of loxoprofen sodium-induced eosinophilic pneumonia that occurred ipsilaterally after VATS lobectomy for lung cancer] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Nihon Koky?ki Gakkai zasshi = the journal of the J

VOLUME: 45

Page Numbers: 799-803

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ISSN: 1343-3490

DAY: 16

MONTH: Oct

YEAR: 2007

[A case of loxoprofen sodium-induced eosinophilic pneumonia that occurred ipsilaterally after VATS lobectomy for lung cancer] Information

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LANGUAGE: jpn

NlmUniqueID: 9808802

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AFFILIATION: First Department of Medicine, School of Medicine, Tokyo Women's Medical University.

Country: Japan

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MEDLINETA: Nihon Kokyuki Gakkai Zasshi

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