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[A case of allergic bronchopulmonary aspergillosis that itraconazole showed a definite effect temporarily]

[A case of allergic bronchopulmonary aspergillosis that itraconazole showed a definite effect temporarily] Research Abstract Details 

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  • [A case of allergic bronchopulmonary aspergillosis that itraconazole showed a definite effect temporarily] Abstract Text:

    zen isobeZen Isobe,tatsuo sugaTatsuo Suga,shigeto hamaguchiShigeto Hamaguchi,kenichirou haraKenichirou Hara,nozomi aokiNozomi Aoki,fumiaki aokiFumiaki Aoki,kana aoyagiKana Aoyagi,manabu uenoManabu Ueno,toshitaka maenoToshitaka Maeno,masahiko kurabayashiMasahiko Kurabayashi,zen isobeZen Isobe,tatsuo sugaTatsuo Suga,shigeto hamaguchiShigeto Hamaguchi,kenichirou haraKenichirou Hara,nozomi aokiNozomi Aoki,fumiaki aokiFumiaki Aoki,kana aoyagiKana Aoyagi,manabu uenoManabu Ueno,toshitaka maenoToshitaka Maeno,masahiko kurabayashiMasahiko Kurabayashi,zen isobeZen Isobe,tatsuo sugaTatsuo Suga,shigeto hamaguchiShigeto Hamaguchi,kenichirou haraKenichirou Hara,nozomi aokiNozomi Aoki,fumiaki aokiFumiaki Aoki,kana aoyagiKana Aoyagi,manabu uenoManabu Ueno,toshitaka maenoToshitaka Maeno,masahiko kurabayashiMasahiko Kurabayashi,

    A 58-year-old woman had a productive cough but not from bronchial asthma. A chest radiograph revealed infiltrative shadows in right middlelung field on September, 2004. Aspergillus fumigatus was detected in a sputum culture. She was treated with oral itraconazole. After the treatment, infiltrative shadows on her chest radiograph disappeared. On October 2005, her peripheral blood showed eosinophilla, a high serum level of total immunoglobulin E (IgE), and a chest radiograph revealed new infiltrative shadows in both lung fields. A chest computed tomography revealed multiple nodular shadows and central bronchiectasis. We detected a mucoid plug which showed a large number of eosinophils pathologically by bronchoscopy. Aspergillus niger was detected in a bronchial lavage fluid. We therefore made a diagnosis of allergic bronchopulmonary aspergillosis (ABPA). The decreases of peripheral blood eosinophils and a serum IgE level were recognized and multiple nodular shadows disappeared by reinstitution of itraconazole. However, a chest computed tomography revealed new infiltrative shadows. Therefore, we treated her with the concomitant administration of oral itraconazole and inhaled corticosteroid. All laboratory data and image findings were improved. It is critical to consider the both aspects of allergy and infection in the treatment for ABPA.

    [A case of allergic bronchopulmonary aspergillosis that itraconazole showed a definite effect temporarily] Publishing Authors By Initials

    z isobeZ Isobe,t sugaT Suga,s hamaguchiS Hamaguchi,k haraK Hara,n aokiN Aoki,f aokiF Aoki,k aoyagiK Aoyagi,m uenoM Ueno,t maenoT Maeno,m kurabayashiM Kurabayashi,z isobeZ Isobe,t sugaT Suga,s hamaguchiS Hamaguchi,k haraK Hara,n aokiN Aoki,f aokiF Aoki,k aoyagiK Aoyagi,m uenoM Ueno,t maenoT Maeno,m kurabayashiM Kurabayashi,z isobeZ Isobe,t sugaT Suga,s hamaguchiS Hamaguchi,k haraK Hara,n aokiN Aoki,f aokiF Aoki,k aoyagiK Aoyagi,m uenoM Ueno,t maenoT Maeno,m kurabayashiM Kurabayashi,

    For similar abstracts research abstracts see: abstracts research

    PUBMED ID PMID:

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    [A case of allergic bronchopulmonary aspergillosis that itraconazole showed a definite effect temporarily] Journal Published:

    PUBLICATION TYPE: Journal Article

    Journal: Arerug? = [Allergy]

    VOLUME: 56

    Page Numbers: 1390-6

    Journal Abbreviation: Arerugi

    ISSN: 0021-4884

    DAY: 6

    MONTH: Nov

    YEAR: 2007

    [A case of allergic bronchopulmonary aspergillosis that itraconazole showed a definite effect temporarily] Information

    Number of References:

    LANGUAGE: jpn

    NlmUniqueID: 241212

    [A case of allergic bronchopulmonary aspergillosis that itraconazole showed a definite effect temporarily] Keywords Mesh Terms:

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    Chemical & Substance for Abstract: [A case of allergic bronchopulmonary aspergillosis that itraconazole showed a definite effect temporarily] Information

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    Grant and Affiliation Information for [A case of allergic bronchopulmonary aspergillosis that itraconazole showed a definite effect temporarily]

    AFFILIATION: Department of Respiratory Medicine, Gunma University Graduate School of Medicine. isobezen@showa.gunma-u.ac.jp

    Country: Japan

    Japan Research PublicationJapan Research Publication

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    MEDLINETA: Arerugi

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