[A case of advanced breast cancer successfully treated with multi-disciplinary therapy and S-1 administration]

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[A case of advanced breast cancer successfully treated with multi-disciplinary therapy and S-1 administration] Abstract Text:

Kenichi Sakurai,Katsuhisa Enomoto,Akira Kitajima,Mayumi Tani,Sadao Amano,Kenichi Sakurai,Katsuhisa Enomoto,Akira Kitajima,Mayumi Tani,Sadao Amano,

We report a case of advanced breast cancer (T4b, N3c, M1) achieving a significant improvement on QOL by multi-disciplinary therapy and S-1 administration. The patient was a 59-year-old woman who had ulcerative breast lump with bleeding. A core needle biopsy for breast tumor led to a diagnosis of an invasive ductal carcinoma negative for estrogen receptor, progesterone receptor, and HER2/neu protein expression. The aspiration biopsy cytology was performed from skin lesion, the diagnosis was class V. She received 6 cycles of tri-weekly CEF (C: 500 mg, E: 60 mg, F: 500 mg/m2) therapy. The effect of the breast tumor was partial response, and the bleeding from the breast lump was improved. But the response from metastatic skin tumor was less satisfactory. We performed a radiation therapy (20 Gy) to metastatic skin tumor, and the lesion disappeared after the radiation therapy. Then, we tried docetaxel, but the side effect appeared. So, we started administering S-1 after docetaxel. One year later, she was estimated to be in the long stable disease. Multi-disciplinary therapy can improve a patient QOL and the clinical outcomes in Stage IV advanced breast cancer.

[A case of advanced breast cancer successfully treated with multi-disciplinary therapy and S-1 administration] Publishing Authors By Initials

K Sakurai,K Enomoto,A Kitajima,M Tani,S Amano,K Sakurai,K Enomoto,A Kitajima,M Tani,S Amano,

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[A case of advanced breast cancer successfully treated with multi-disciplinary therapy and S-1 administration] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Gan to kagaku ryoho. Cancer & chemotherapy

VOLUME: 34

Page Numbers: 2065-7

Journal Abbreviation: Gan To Kagaku Ryoho

ISSN: 0385-0684

DAY: 28

MONTH: Nov

YEAR: 2007

[A case of advanced breast cancer successfully treated with multi-disciplinary therapy and S-1 administration] Information

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LANGUAGE: jpn

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AFFILIATION: Division of Breast and Endocrine Surgery, Dept. of Surgery, Nihon University School of Medicine.

Country: Japan

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MEDLINETA: Gan To Kagaku Ryoho

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