A Canadian tertiary care centre study of maternal and umbilical cord cotinine levels as markers of smoking during pregnancy: relationship to neonatal effects.

A Canadian tertiary care centre study of maternal and umbilical cord cotinine levels as markers of smoking during pregnancy: relationship to neonatal effects. Research Abstract Details 

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A Canadian tertiary care centre study of maternal and umbilical cord cotinine levels as markers of smoking during pregnancy: relationship to neonatal effects. Abstract Text:

S L Perkins,J M Belcher,J F Livesey,

This study describes the prevalence of smoking among 3,220 pregnant women. Maternal and umbilical cord cotinine levels were compared with the women's self-reported cigarette consumption, infant birth weight and antepartum and perinatal complications. Of the women who reported themselves as being active smokers (23%), 76% had a partner who smoked, and 38% reported exposure to environmental smoke in the workplace. Only 15% of nonsmokers had a partner who smoked, and 13% reported workplace exposure. The mean number of cigarettes/day was 20.5 (95% CI 19.6-21.4). The relative risk of having a small-for-gestational-age infant was significantly higher in smokers for mothers of both preterm (34-36 wks, RR = 3.38, 95% CI 1.25-9.16) and term babies (> or = 37 wks, RR = 2.04, 95% CI 1.58-2.63). Mean infant birth weight was 207 g lighter in the infants of smokers (p < 0.001) and was inversely correlated to maternal serum cotinine level. Birth weight dropped by 0.99 g for every 1 ug/L increase in cotinine (r = -0.19, p < 0.01).

A Canadian tertiary care centre study of maternal and umbilical cord cotinine levels as markers of smoking during pregnancy: relationship to neonatal effects. Publishing Authors By Initials

SL Perkins,JM Belcher,JF Livesey,

For similar behavior and behavior mechanisms: behavior: habits: smoking research abstracts see: behavior and behavior mechanisms: behavior: habits: smoking research

PUBMED ID PMID:

MEDLINE DATE: 1997 Jul-Aug

A Canadian tertiary care centre study of maternal and umbilical cord cotinine levels as markers of smoking during pregnancy: relationship to neonatal effects. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Canadian journal of public health. Revue canadienn

VOLUME: 88

Page Numbers: 232-7

Journal Abbreviation:

ISSN: 0008-4263

DAY: 13

MONTH: 02

YEAR: 2008

A Canadian tertiary care centre study of maternal and umbilical cord cotinine levels as markers of smoking during pregnancy: relationship to neonatal effects. Information

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LANGUAGE: eng

NlmUniqueID: 372714

A Canadian tertiary care centre study of maternal and umbilical cord cotinine levels as markers of smoking during pregnancy: relationship to neonatal effects. Keywords Mesh Terms:

KEYWORDS: Smoking

MESH TERMS: metabolism

Chemical & Substance for Abstract: A Canadian tertiary care centre study of maternal and umbilical cord cotinine levels as markers of smoking during pregnancy: relationship to neonatal effects. Information

Substance Name: Cotinine

Registry Number: 486-56-6

Grant and Affiliation Information for A Canadian tertiary care centre study of maternal and umbilical cord cotinine levels as markers of smoking during pregnancy: relationship to neonatal effects.

AFFILIATION: Department of Laboratory Medicine, Ottawa Civic Hospital, Ontario. slperkins@civich.ottawa.on.ca

Country: CANADA

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MEDLINETA: Can J Public Health

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