[5-Aminolevulinic acid esters based photodynamic therapy]

[5-Aminolevulinic acid esters based photodynamic therapy] Research Abstract Details 

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[5-Aminolevulinic acid esters based photodynamic therapy] Abstract Text:

Sujuan Zhang,Zhenxi Zhang,Dazong Jiang,

As exogenous ALA (5-aminolevulinic acid) esters can induce the production and accumulation of endogenous photosensitizer PpIX (protoporphyrin IX) in tumor tissues more effectively, they have been the most active photosensitizer prodrug in PDT(photodynamic therapy) field. In this article, along with the procedure of ALA esters based PDT, some primary mechanism and experimental results were considered, which include: first, cellular uptake of ALA esters and its conversion into ALA; second, the production and accumulation of endogenous photosensitizer PpIX induced by eNdogenous ALA esters; last, the photosensitization of PpIX.

[5-Aminolevulinic acid esters based photodynamic therapy] Publishing Authors By Initials

S Zhang,Z Zhang,D Jiang,

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[5-Aminolevulinic acid esters based photodynamic therapy] Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Sheng wu yi xue gong cheng xue za zhi = Journal of

VOLUME: 19

Page Numbers: 310-4

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ISSN: 1001-5515

DAY: 12

MONTH: Jun

YEAR: 2002

[5-Aminolevulinic acid esters based photodynamic therapy] Information

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LANGUAGE: chi

NlmUniqueID: 9426398

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Grant and Affiliation Information for [5-Aminolevulinic acid esters based photodynamic therapy]

AFFILIATION: Institute of Biomedical Engineering, Xi'an Jiaotong University, Xi'an 710049.

Country: China

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MEDLINETA: Sheng Wu Yi Xue Gong Cheng Xue

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