3D excretory MR urography: improved image quality with intravenous saline and diuretic administration.

3D excretory MR urography: improved image quality with intravenous saline and diuretic administration. Research Abstract Details 

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3D excretory MR urography: improved image quality with intravenous saline and diuretic administration. Abstract Text:

F Bilge Ergen,Hero K Hussain,Ruth C Carlos,Timothy D Johnson,Saroja Adusumilli,William J Weadock,Melvyn Korobkin,Isaac R Francis,

PURPOSE: To assess the effect of diuretic administration on the image quality of excretory magnetic resonance urography (MRU) obtained following intravenous hydration, and to determine whether intravenous hydration alone is sufficient to produce diagnostic quality studies of nondilated upper tracts. MATERIALS AND METHODS: A total of 22 patients with nondilated upper tracts were evaluated with contrast-enhanced MRU. All patients received 250 mL of saline intravenously immediately prior to the examination. A total of 11 patients received 10-20 mg furosemide in addition to saline. Imaging was performed with a three-dimensional (3D) and two-dimensional (2D) breathhold spoiled gradient-echo sequences. Excretory MRU images were acquired five minutes after the administration of 0.1 mmol/kg gadolinium and were independently reviewed by two radiologists, who were blinded to the MRU technique. Readers evaluated the calyces, renal pelvis, and ureters qualitatively for degree of opacification, distention, and artifacts on a four-point scale. Statistical analysis was performed using a permutation test. RESULTS: There was no significant disagreement between the two readers (P=0.14). Furosemide resulted in significant improvement in calyceal and renal pelvis distention (P<0.005), and significant artifact reduction in all upper tract segments (P<0.001) compared to the effect of saline alone. CONCLUSION: Intravenous furosemide significantly improves the image quality of excretory MRU studies obtained following intravenous hydration. Intravenous saline alone is insufficient to produce diagnostic quality studies of the non-dilated upper tracts.

3D excretory MR urography: improved image quality with intravenous saline and diuretic administration. Publishing Authors By Initials

FB Ergen,HK Hussain,RC Carlos,TD Johnson,S Adusumilli,WJ Weadock,M Korobkin,IR Francis,

For similar diagnosis: diagnostic techniques and procedures: diagnostic imaging: radiography: urography research abstracts see: diagnosis: diagnostic techniques and procedures: diagnostic imaging: radiography: urography research

PUBMED ID PMID:

MEDLINE DATE:

3D excretory MR urography: improved image quality with intravenous saline and diuretic administration. Journal Published:

PUBLICATION TYPE: Research Support, N.I.H., Extr

Journal: Journal of magnetic resonance imaging : JMRI

VOLUME: 25

Page Numbers: 783-9

Journal Abbreviation:

ISSN: 1053-1807

DAY: 3

MONTH: Apr

YEAR: 2007

3D excretory MR urography: improved image quality with intravenous saline and diuretic administration. Information

Number of References:

LANGUAGE: eng

NlmUniqueID: 9105850

3D excretory MR urography: improved image quality with intravenous saline and diuretic administration. Keywords Mesh Terms:

KEYWORDS: Urography

MESH TERMS: methods

Chemical & Substance for Abstract: 3D excretory MR urography: improved image quality with intravenous saline and diuretic administration. Information

Substance Name: Sodium Chloride

Registry Number: 7647-14-5

Grant and Affiliation Information for 3D excretory MR urography: improved image quality with intravenous saline and diuretic administration.

AFFILIATION: Department of Radiology/MRI, University of Michigan Health System, Ann Arbor, Michigan 48109-0003, USA.

Country: United States

AGENCY: United States NCRR

GRANT: K12 RR017607-01

ACRONYM: RR

MEDLINETA: J Magn Reson Imaging

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