1-year treatment with recombinant somatropin in prepubertal and pubertal growth hormone deficient patients: results from a French multicentre trial.

1-year treatment with recombinant somatropin in prepubertal and pubertal growth hormone deficient patients: results from a French multicentre trial. Research Abstract Details 

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1-year treatment with recombinant somatropin in prepubertal and pubertal growth hormone deficient patients: results from a French multicentre trial. Abstract Text:

J C Job,P Rochiccioli,R Rappaport,M C Raux-Demay,C Ponte,J Juif,M Colle,M Lecornu,B Leheup,P Garandeau,

In this French study with recombinant somatropin, the stimulation of growth in 32 prepubertal (age 10.0 +/- 3.5 years; mean +/- SD) and 19 pubertal (age 14 +/- 1.5 years) GH deficient children was compared; the stimulation of growth was similarly good in the two groups. The height velocity SD scores increased from -2.5 +/- 1.7 and -0.9 +/- 1.5 to 2.2 +/- 1.9 and 1.6 +/- 1.6 in prepubertal and pubertal children, respectively. Expressed as cm/year, these correspond to increases from 3.2 +/- 1.3 cm/year and 4.1 +/- 1.2 cm/year to 8.1 +/- 1.5 cm/year and 8.6 +/- 1.9 cm/year in the prepubertal and pubertal patients, respectively. Safety and tolerance were good and the immunogenicity of Genotonorm was low.

1-year treatment with recombinant somatropin in prepubertal and pubertal growth hormone deficient patients: results from a French multicentre trial. Publishing Authors By Initials

JC Job,P Rochiccioli,R Rappaport,MC Raux-Demay,C Ponte,J Juif,M Colle,M Lecornu,B Leheup,P Garandeau,

For similar proteins: recombinant proteins research abstracts see: proteins: recombinant proteins research

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1-year treatment with recombinant somatropin in prepubertal and pubertal growth hormone deficient patients: results from a French multicentre trial. Journal Published:

PUBLICATION TYPE: Multicenter Study

Journal: Acta paediatrica Scandinavica. Supplement

VOLUME: 347

Page Numbers: 187-90

Journal Abbreviation:

ISSN: 0300-8843

DAY: 20

MONTH: 02

YEAR: 1988

1-year treatment with recombinant somatropin in prepubertal and pubertal growth hormone deficient patients: results from a French multicentre trial. Information

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LANGUAGE: eng

NlmUniqueID: 173166

1-year treatment with recombinant somatropin in prepubertal and pubertal growth hormone deficient patients: results from a French multicentre trial. Keywords Mesh Terms:

KEYWORDS: Recombinant Proteins

MESH TERMS: immunology

Chemical & Substance for Abstract: 1-year treatment with recombinant somatropin in prepubertal and pubertal growth hormone deficient patients: results from a French multicentre trial. Information

Substance Name: Growth Hormone

Registry Number: 9002-72-6

Grant and Affiliation Information for 1-year treatment with recombinant somatropin in prepubertal and pubertal growth hormone deficient patients: results from a French multicentre trial.

AFFILIATION: French Multicentre Trial Group, Paris, France.

Country: SWEDEN

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MEDLINETA: Acta Paediatr Scand Suppl

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