Progressive multifocal leukoencephalopathy and CD4+ T-lymphocytopenia in a patient with Sjögren syndrome.

Progressive multifocal leukoencephalopathy and CD4+ T-lymphocytopenia in a patient with Sjögren syndrome. Research Abstract Details 

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Progressive multifocal leukoencephalopathy and CD4+ T-lymphocytopenia in a patient with Sjögren syndrome. Abstract Text:

Yuichi Hayashi,Akio Kimura,Shimon Kato,Akihiro Koumura,Takeo Sakurai,Yuji Tanaka,Isao Hozumi,Yuji Sunden,Yasuko Orba,Hirofumi Sawa,Hitoshi Takahashi,Takashi Inuzuka,

We report progressive multifocal leukoencephalopathy (PML) and CD4+ T-lymphocytopenia in a 71-year-old man with Sjögren syndrome (SjS). The patient was admitted to our hospital because of progressive dementia and gait disturbance. T2-weighted MR images showed high-intensity lesions in his left frontal white matter thalamus, cerebellum and brainstem. A pathological diagnosis of PML was made by brain biopsy. SjS is frequently accompanied with immunological complications; however, there are few reports on PML in patients with SjS. Recently, isolated CD4+ T-lymphocytopenia is reported to be one of the based immunological conditions associated with the development of PML. In the present case, CD4+ T-lymphocytopenia was also observed on admission, which is also associated with SjS.

Progressive multifocal leukoencephalopathy and CD4+ T-lymphocytopenia in a patient with Sjögren syndrome. Publishing Authors By Initials

Y Hayashi,A Kimura,S Kato,A Koumura,T Sakurai,Y Tanaka,I Hozumi,Y Sunden,Y Orba,H Sawa,H Takahashi,T Inuzuka,

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Progressive multifocal leukoencephalopathy and CD4+ T-lymphocytopenia in a patient with Sjögren syndrome. Journal Published:

PUBLICATION TYPE: Journal Article

Journal: Journal of the neurological sciences

VOLUME: 268

Page Numbers: 195-8

Journal Abbreviation: J. Neurol. Sci.

ISSN: 0022-510X

DAY: 29

MONTH: 01

YEAR: 2008

Progressive multifocal leukoencephalopathy and CD4+ T-lymphocytopenia in a patient with Sjögren syndrome. Information

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LANGUAGE: eng

NlmUniqueID: 375403

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Grant and Affiliation Information for Progressive multifocal leukoencephalopathy and CD4+ T-lymphocytopenia in a patient with Sjögren syndrome.

AFFILIATION: Department of Neurology and Geriatrics, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu, Gifu 501-1194, Japan.

Country: Netherlands

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MEDLINETA: J Neurol Sci

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