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Target Specific Whole Cell Assay for Antibacterial Drug Discovery Protocol - Details

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Protocols » Listing Details
ID:3582
Title: Target Specific Whole Cell Assay for Antibacterial Drug Discovery Protocol - http://www.natureprotocols.com/2006/06/23/a_targetspecific_whole_cell_as.php
Description:Protocol describes a target selective S. aureus whole cell assay that combines agar-diffusion and protein over expression techniques.  This agar based two-plate differential sensitivity assay was used to help confirm the newly discovered antibiotic platensimycin inhibited bacterial growth by specifically targeting the essential FASII enzyme FabF6.
Category:Pharmacology and Toxicology Protocols: Drug Discovery
Link Owner:
Date Added:July 10, 2008 12:44:53 PM
Number Hits:17
 

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