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Conditional Ablation of Stat3 Socs3 Discloses the Dual Role for Reactive Astrocytes - Details

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Protocols » Listing Details
ID:3516
Title: Conditional Ablation of Stat3 Socs3 Discloses the Dual Role for Reactive Astrocytes - http://www.natureprotocols.com/2006/06/30/conditional_ablation_of_stat3s.php
Description:Conditional ablation of stat3/socs3 discloses the dual role for reactive astrocytes after spinal cord injury. The current protocol demonstrates that reactive astrocytes play a crucial role in wound healing and functional recovery by using mice with a selective deletion of the signal transducer and activator of transcription-3 (STAT3) or suppression of cytokine signaling-3 (SOCS3) under the control of Nestin gene promoter/enhancer (STAT3N–/–, SOCS3N–/–).
Category:Neuroscience Protocols: Neuronal Cell Culture Protocols: Rat Neuronal Cell Culture Protocols
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Date Added:June 24, 2008 02:04:54 AM
Number Hits:17
 

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