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A Computational Screening protocol for Antifreeze/Ice-Structuring Proteins - Details

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Protocols » Listing Details
ID:1979
Title: A Computational Screening protocol for Antifreeze/Ice-Structuring Proteins - http://www.natureprotocols.com/2006/08/17/afpredictor_a_computational_sc.php
Description:Using AFPredictor, it was demonstrated that ‘ordered surface carbons’ (OSCs) are a distinguishing feature of AFPs and, more specifically, their ice-binding surfaces. AFPredictor identified AFPs from within a large set of structures with greater than 99% specificity. Furthermore, it was used to identify a novel ice-binding protein by screening a library of homology modeled structures based on cDNA sequences obtained from cold-acclimated winter rye (Secale cereale).
Category:Bioinformatics
Link Owner:
Date Added:December 14, 2007 10:18:06 AM
Number Hits:12
 

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