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Protocol for Conditional Ablation of stat3/socs3 Discloses the Dual Role for Reactive Astrocytes - Details

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Protocols » Listing Details
ID:1277
Title: Protocol for Conditional Ablation of stat3/socs3 Discloses the Dual Role for Reactive Astrocytes - http://www.natureprotocols.com/2006/06/30/conditional_ablation_of_stat3s.php
Description:Protocol demonstrates that reactive astrocytes play a crucial role in wound healing and functional recovery by using mice with a selective deletion of the signal transducer and activator of transcription-3 (STAT3) or suppression of cytokine signaling-3 (SOCS3) under the control of Nestin gene promoter/enhancer (STAT3N–/–, SOCS3N–/–). Procedure includes: Surgical procedures, Functional evaluation, Immunohistochemistry, In vitro migration assay.
Category:Signalling Signal Transduction Protocols
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Date Added:September 18, 2007 02:13:08 AM
Number Hits:13
 

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