Peptides

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Applications of Peptides

Recently there has been an explosion of peptide utilization in all science fields, thus the growing demand for the synthesis of synthetic peptides. Peptide have been proved to act as great probes for the study of protein-protein interactions, the binding of ligands to the extracellular domains of cell surface proteins and receptors, studying epitopes in immunology or antibody-antigen interactions, the study of inhibitory peptides on protein functions such as inhibition of cancer-inducing proteins, and enzyme-protein substrate interactions to mention a few. Also the design and application of fluorescent substrate-based peptides can be used to determine the selectivity and activity of peptidases.

Synthetic peptides can be utilized as probes in all the previously mentioned scenarios as they all involve amino acid residue interactions . Although many of these protein interactions often involve amino acid residues from distant protein domains, there are many examples where short stretches of amino acids are vital for protein-protein interactions (acting as contiguous epitopes) and thus allow the application and the use of synthetic peptides for the study of a broad range of biological phenomena.

The creation of antibodies specific for a protein is quickly done using peptides. Peptides will not fold similarly to native proteins (due to their smaller size and lack of many native residues), however they can be useful in the generation of antibodies.

Peptide Forum Topics

recommend a copper peptide facial cream? I am looking for a copper peptide cream to help improve some roller scars left from acne from childhood. Have been searching the net but im unable to...
Which of the following is a function of a signal peptide? Question 2 options: 1) To bind RNA polymerase to DNA and initiate transcription
How do C and N terminal ends react with each other in the joining of 2 peptides? In the joining of two peptides to form a polypeptide, the N-terminal end of one peptide will react with the _______ of the other peptide forming a(n)...
The third amino acid in the peptidoglycan cross-linking tetra-peptide chain? The third amino acid in the peptidoglycan cross-linking tetra-peptide chain is either diaminopimelic acid, or lysine. These amino acids are located...
Physical Chemistry - Peptides? The peptide Special-K forms an a-helix that is broken at high temperatures. The fraction of peptide in the a-helical form (fraction = moles a-helical...
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