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Genome duplication and splitting of protein function

Genome duplication and splitting of protein function - Zebrafish Forum

Genome duplication and splitting of protein function - Zebrafish Danio Rerio Forum. Discuss zebrafish, aquarium culture and molecular biology lab specimens.


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Old 07-26-2010, 01:39 PM
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Default Genome duplication and splitting of protein function



Hi all,

I heard somebody saying that in Zebrafish, because of the teleost genome duplication, a function that is fulfilled by a single protein in other species is often fulfilled by two similar proteins (paralogues).

E.g., protein X acts in the CNS and PNS in mouse - in the zebrafish, protein X1 will act in the CNS and X2 in the PNS.

Could somebody please say if this is really the case, and if possible give me examples or a reference?!

Thank you very much!

Roland
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duplication , function , genome , protein , splitting


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