Hi rp !
Don't know exactly how that work but from what I've read, LTX (or L2000 or any lipid reagent) and nucleic acids forms lipoplex. Then that lipoplex combines with the magnetic nanoparticle (Combimag).
Under your cell plate you put a strong magnetic plate that attract the magnetic particles linked to lipoplex.
The point is, 30 min of incubation are suffisant to reach a high transfection efficiency, so you can perform a medium change very earlier, compared to the 6h needed with LTX use. So the toxicity is reduced while efficiency is amplified.
I've tested Combimag in association with either L2000 and LTX and it works very well
pv me if you need more info