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molecule2005 12-19-2006 07:53 AM

Phosphatase Inhibitors
 
Hey everyone!

does anyone have a list of good phosphatase inhibitors they use?
please list them here.

Also if you know which phosphatases they inhibit (serine, tyrosine ?) that would be greatly appreciated!


thanks :)

tuttu 01-05-2007 02:57 PM

Re: Phosphatase Inhibitors
 
HI,

U may chk this link below, its got some info,

[Only registered and activated users can see links. Click Here To Register...]

cheers

Cancerinform 05-17-2009 08:53 AM

Re: Phosphatase Inhibitors
 
The most potent phosphatase inhibitor is Calyculin A.

ken_aurora 02-23-2011 03:27 AM

Re: Phosphatase Inhibitors
 
There are so many phosphatase inhibitors.I don't what inhibitors you want to know.
Actually,Scientists always use phosphatase Inhibitor cocktail set.
I will list all the phosphatase inhibitors which I know.
(1)bpv
(2)calcineurin autoinhibitory peptide
(3)calyculin A
(4)BN82002
(5)NSC 663284
(6)cyclosprin A
(7)DARPP-32
(8)deltamethrin
(9)dephostatin
(10)3,4-dephostatin

tracyzh130 02-17-2012 05:52 AM

Re: Phosphatase Inhibitors
 
Sodium orthovanadate is the chemical compound Na3VO4 and contains the tetrahedral VO43-. It is an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and a number of ATPases, most likely acting as a phosphate analogue.

mkc3 09-05-2012 03:45 PM

Re: Phosphatase Inhibitors
 
No one phosphatase inhibitor on its own will inhibit all classes of phosphatases. I use a combination of sodium fluoride, sodium pyrophosphate, sodium beta-glycerophosphate, and sodium orthovanadate to inhibit phosphatases in cell lysates generated from S. cerevisiae.


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