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Signalling Biology Signalling is an integral part of the cell neural network. Phosphorylation and other protein modifications modulate this interaction. Post and discuss the study of protein-protein interactions, and signalling biology protocols and science here.


For help: about AXIN2 activation by Wnt signaling

For help: about AXIN2 activation by Wnt signaling - Signalling Biology

For help: about AXIN2 activation by Wnt signaling - Signalling is an integral part of the cell neural network. Phosphorylation and other protein modifications modulate this interaction. Post and discuss the study of protein-protein interactions, and signalling biology protocols and science here.


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Old 08-06-2010, 04:58 PM
Pipette Filler
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Smile For help: about AXIN2 activation by Wnt signaling



Does anyone know in which cell line AXIN2 may be activated significantly by Wnt signaling? I need this type of cell line to investigate chromasome modification around AXIN2 locus by Wnt signaling. Some people told me no AXIN2 activation occurs in HEK293T cells, so I should find another one.
All the best and many thanks in advance!
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Old 11-09-2011, 11:18 PM
Pipette Filler
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Default Re: For help: about AXIN2 activation by Wnt signaling

Depends which Wnt you are using. Wnt3a will absolutely upregulate Axin2 in 293T cells.
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