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Signalling Biology Signalling is an integral part of the cell neural network. Phosphorylation and other protein modifications modulate this interaction. Post and discuss the study of protein-protein interactions, and signalling biology protocols and science here.


how to test the components of golgi-plasma membrane pathway involved?b

how to test the components of golgi-plasma membrane pathway involved?b - Signalling Biology

how to test the components of golgi-plasma membrane pathway involved?b - Signalling is an integral part of the cell neural network. Phosphorylation and other protein modifications modulate this interaction. Post and discuss the study of protein-protein interactions, and signalling biology protocols and science here.


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Old 05-29-2009, 12:07 PM
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Default how to test the components of golgi-plasma membrane pathway involved?b



Hi all,
I'm pretty new in the cell-signaling field so I need help.
I have determined that my chemical downregulates the fully glycosylated membrane version of a receptor, but not the partially glycosylated precursor (which is apparently in the Golgi, a speculation based on a few papers).

How do I attempt to investigate the actual components of the pathway involved?
I work with a mammalian system, non-immortal cells. There are a couple of cell models but the pathway may not be identical.

Please, any idea will help
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components , downregulation , glycosylation , golgiplasma , involvedb , membrane , pathway , receptor , test


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