| | Re: As a bio major, should i be concerned with working with HIV?
It's good to have a healthy concern for safety. It helps you develop and maintain proper procedures for dealing with potentially hazardous materials.
If you follow proper BSL-2 procedures, the chances that you'll contract a pathogen are very, very low. You're probably much more likely to get hit by a bus on your way to work than to get HIV at work.
There are also further steps you can take that aren't specifically included in the BSL-2 specification, sort of "BSL-2+". For example, when working with any kind of virus, I always wear a face mask and completely avoid using sharps or glass, while for standard BSL-2 work (ie. culture of human cells) I don't wear a mask and I use glass pipettes. Most labs have their own specific safety protocols that you can ask about before accepting a position there, to make sure you're comfortable with their level of risk management.