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Can RNAi treat recessively-inherited genetic diseases?

Can RNAi treat recessively-inherited genetic diseases? - RNAi and SiRNA Forum

Can RNAi treat recessively-inherited genetic diseases? - Discuss and Post Questions in this forum about RNA interference and siRNA. RNAi and siRNA transfection, inhibition of endogenous genes, and miRNA and shRNA.


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Old 04-05-2014, 09:02 AM
Pipette Filler
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Default Can RNAi treat recessively-inherited genetic diseases?



RNAinterferencehasbeeninvestigatedforitstherapeuti cpropertiesintreating diseases.ProtocolshavebeendevelopedtouseRNAitotrea tdiseasessuch asmacular degeneration,Huntington’sdisease,andsomeformsofcan cer.The interestingthingtonoteis thatthese above-mentionedgeneticdiseasesarealldominantly-inherited;thatis,theyresult fromtheeffectsofonemutantallele.Noresearcherhasyet attemptedtouseRNAitotreat recessively-inheritedgeneticdiseases.ExplainwhyyouthinkthatRNA icanbeeffective against dominantformsofadiseaseandnotrecessiveforms.
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Old 04-16-2014, 06:09 PM
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Default Re: Can RNAi treat recessively-inherited genetic diseases?

It depends on the disease.
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diseases , genetic , recessivelyinherited , rnai , treat


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